Titre
Magnetic resonance imaging with gadolinium contrast agent in small deep (lacunar) cerebral infarcts.
Type
article
Institution
UNIL/CHUV/Unisanté + institutions partenaires
Périodique
Auteur(s)
Regli, L.
Auteure/Auteur
Regli, F.
Auteure/Auteur
Maeder, P.
Auteure/Auteur
Bogousslavsky, J.
Auteure/Auteur
Liens vers les personnes
Liens vers les unités
ISSN
0003-9942
Statut éditorial
Publié
Date de publication
1993-02
Volume
50
Numéro
2
Première page
175
Dernière page/numéro d’article
180
Peer-reviewed
Oui
Langue
anglais
Notes
Regli, L Regli, F Maeder, P Bogousslavsky, J United states Archives of neurology Arch Neurol. 1993 Feb;50(2):175-80. --- Old month value: Feb
Résumé
OBJECTIVE--To assess gadolinium-diethylenetriamine-pentaacetic acid (Gd-DTPA) contrast-enhanced magnetic resonance (MR) imaging as an index of recent symptomatic small deep cerebral infarcts (SDCIs). DESIGN--Prospective case series. SETTINGS--Primary-care center. PATIENTS--Thirty-one consecutive patients presenting with the clinical diagnosis of SDCI in the territory of the perforators of the internal carotid artery or the vertebrobasilar system and confirmed by MR imaging. INTERVENTION--Rapid intravenous infusion of Gd-DTPA 5 to 10 minutes prior to acquisition of T1-weighted images. MAIN OUTCOME MEASURES--Precise clinicotopographic correlation on MR scans. RESULTS--Non-contrast-enhanced MR imaging allowed precise clinicotopographic correlation in five (38%) of 13 patients with SDCI symptoms in the internal carotid artery territory. After Gd-DTPA administration, precise clinicotopographic correlation improved in 11 (85%) of 13 patients. In five patients, precise correlation was possible only after Gd-DTPA enhancement. Nonenhanced MR imaging allowed precise clinicotopographic correlation in 15 (83%) of 18 patients with SDCI symptoms in the vertebrobasilar territory. After Gd-DTPA administration, we could establish precise clinicotopographic correlation in all patients with SDCIs in the vertebrobasilar territory. In three patients, precise correlation was possible only after Gd-DTPA contrast enhancement. In seven (23%) of 31 patients, Gd-DTPA failed to enhance symptomatic lesion: in five patients MR scans were performed early (less than 7 days) and in two patients later in the course (greater than 7 days). CONCLUSIONS--Although Gd-DTPA administration is unlikely to improve the sensitivity of MR images in visualizing SDCIs, it significantly improves the rate of precise clinicoanatomic correlation. All enhancing lesions showed precise clinicotopographic correlation. Enhancement may be absent in the acute phase (less than 7 days).
PID Serval
serval:BIB_1298103C4CD4
PMID
Date de création
2008-04-11T07:23:26.796Z
Date de création dans IRIS
2025-05-20T14:20:49Z