Titre
Differential recruitment of the speech processing system in healthy subjects and rehabilitated cochlear implant patients.
Type
article
Institution
Externe
Périodique
Auteur(s)
Giraud, A.L.
Auteure/Auteur
Truy, E.
Auteure/Auteur
Frackowiak, R.S.
Auteure/Auteur
Grégoire, M.C.
Auteure/Auteur
Pujol, J.F.
Auteure/Auteur
Collet, L.
Auteure/Auteur
Liens vers les personnes
ISSN
0006-8950
Statut éditorial
Publié
Date de publication
2000
Volume
123 ( Pt 7)
Première page
1391
Dernière page/numéro d’article
1402
Langue
anglais
Notes
Publication types: Clinical Trial ; Journal Article ; Research Support, Non-U.S. Gov'tPublication Status: ppublish
Résumé
Differences in cerebral activation between control subjects and post-lingually deaf rehabilitated cochlear implant patients were identified with PET under various speech conditions of different linguistic complexity. Despite almost similar performance in patients and controls, different brain activation patterns were elicited. In patients, an attentional network including prefrontal and parietal modality-aspecific attentional regions and subcortical auditory regions was over-activated irrespective of the nature of the speech stimuli and during expectancy of speech stimuli. A left temporoparietal semantic region was responsive to meaningless stimuli (vowels). In response to meaningful stimuli (words, sentences, story), left middle and inferior temporal semantic regions and posterior superior temporal phonological regions were under-activated in patients, whereas anterior superior temporal phonological regions were over-activated. These differences in the recruitment of the speech comprehension system reflect the alternative neural strategies that permit speech comprehension after cochlear implantation.
PID Serval
serval:BIB_BFB8366CF1CF
PMID
Open Access
Oui
Date de création
2011-09-12T18:51:56.554Z
Date de création dans IRIS
2025-05-21T03:56:00Z