Titre
Determinants of Metabolic Health Across Body Mass Index Categories in Central Europe: A Comparison Between Swiss and Czech Populations.
Type
article
Institution
UNIL/CHUV/Unisanté + institutions partenaires
Périodique
Auteur(s)
Kunzova, S.
Auteure/Auteur
Maugeri, A.
Auteure/Auteur
Medina-Inojosa, J.
Auteure/Auteur
Lopez-Jimenez, F.
Auteure/Auteur
Vinciguerra, M.
Auteure/Auteur
Marques-Vidal, P.
Auteure/Auteur
Liens vers les personnes
Liens vers les unités
ISSN
2296-2565
Statut éditorial
Publié
Date de publication
2020
Volume
8
Première page
108
Peer-reviewed
Oui
Langue
anglais
Notes
Publication types: Journal Article
Publication Status: epublish
Publication Status: epublish
Résumé
Comparisons among countries can help to identify opportunities for the reduction of inequalities in cardiometabolic health. The present cross-sectional analysis and meta-analysis aim to address to what extent obesity traits, socioeconomic, and behavioral factors determine poor metabolic health across body mass index (BMI) categories in two urban population-based samples from Central Europe. Data from the CoLaus (~6,000 participants; Lausanne, Switzerland) and the Kardiovize Brno 2030 (~2,000 participants; Brno, Czech Republic) cohorts. For each cohort, logistic regression analyses were performed to identify the main determinants of poor metabolic health overall and stratified by body mass index (BMI) categories. The results of each cohort were then combined in a meta-analysis. We first observed that waist circumference and body fat mass were associated with metabolic health, especially in non-obese individuals. Moreover, increasing age, being male, having low-medium educational level, abdominal obesity, and high body fat mass were the main determinants of the metabolically unhealthy profile in both cohorts. Meta-analysis stratified by BMI categories confirmed the previous results with slight differences across BMI categories. In fact, increasing age and being male were the main determinants of poor metabolic health independent of obesity status. In contrast, low educational level and current smoking were associated with poor metabolic health only in non-obese individuals. In line, public health strategies against obesity and related comorbidities should aim to improve social conditions and to promote healthy lifestyles before the progression of metabolic disorders.
PID Serval
serval:BIB_44AE00F8B785
PMID
Open Access
Oui
Date de création
2020-04-25T16:08:18.424Z
Date de création dans IRIS
2025-05-20T18:27:13Z
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Nom
Frontiers 2020.pdf
Version du manuscrit
published
Licence
https://creativecommons.org/licenses/by/4.0
Taille
611.51 KB
Format
Adobe PDF
PID Serval
serval:BIB_44AE00F8B785.P001
URN
urn:nbn:ch:serval-BIB_44AE00F8B7853
Somme de contrôle
(MD5):3c3f0ec5a949dd5652858999944152c0