Titre
Dynamic contrast-enhanced MR imaging : a reliable diagnostic tool for recurrent head and neck tumors : B-184
Type
poster de conférence/colloque
Institution
UNIL/CHUV/Unisanté + institutions partenaires
Série
European Radiology
Auteur(s)
Kamel, E.
Auteure/Auteur
Pasche, P.
Auteure/Auteur
Meuli, R.
Auteure/Auteur
Hauser, P.
Auteure/Auteur
Borchardt, I.
Auteure/Auteur
Schnyder, P.
Auteure/Auteur
Duvoisin, B.
Auteure/Auteur
Liens vers les personnes
Liens vers les unités
Titre du livre ou conférence/colloque
ECR 2009, European Congress of Radiology
Adresse
Vienna, Austria, March 6-10 2009
ISBN
0938-7994
Statut éditorial
Publié
Date de publication
2009
Volume
19
Première page
S180
Peer-reviewed
Oui
Langue
anglais
Notes
Purpose: To investigate the role of Dynamic Contrast-Enhanced MR Imaging (DCE-MRI) in the follow-up of patients with head and neck tumors. Methods and Materials: Twenty-seven patients were recruited. DCE-MRI was performed as a part of regular posttherapy follow-up (n = 20) or for clinical suspicion of local disease recurrence (n = 7). Axial dynamic T1-weighted fat sat sequences were performed in a 3-T MR scanner for a total duration of 10 minutes after contrast administration. An operator-defined region of interest was placed in the maximal enhancement area(s) of the tumor bed. A time-intensity curve was constructed. The time to maximal enhancement (Tmax), enhancement ratio at 3 min (ER3min), and washout ratio at 10 min (WR10min) were measured. Per-lesion DCE-MRI findings were correlated with histologic analysis or with clinical and radiological follow-up. Results: There was a significant difference between Tmax, ER3min and WR10min of recurrent lesions and those of posttherapy tissue remodeling (2.2 min, 19%, and 20% vs. 8.3 min, 12%, and 6%, P < 0.05). Among 12 recurrent lesions in 9 patients, DCE-MRI detected 11/12 (91%) of these foci. One false negative result was due to microscopic disease residue. Two radionecrotic lesions were responsible for false positive DCE-MRI results in 2 patients. In the remaining 16 patients, true negative DCE-MRI findings were confirmed. Accordingly, the sensitivity, specificity, and accuracy of DCE-MRI were 91%, 89% and 90%, respectively. Conclusion: DCE-MRI can be integrated in the diagnostic work-up of patients with or without clinical or radiological suspicion of recurrent head and neck tumors.
PID Serval
serval:BIB_AF899E8522E1
Date de création
2009-03-11T11:21:24.061Z
Date de création dans IRIS
2025-05-20T21:39:24Z