Titre
Le rein de l'enfant face à la chimiothérapie [The kidney in children under chemotherapy].
Type
synthèse (review)
Institution
UNIL/CHUV/Unisanté + institutions partenaires
Périodique
Revue Médicale de la Suisse Romande
Auteur(s)
Cachat, F.
Auteure/Auteur
Guignard, J.P.
Auteure/Auteur
Liens vers les personnes
Liens vers les unités
ISSN
0035-3655
Statut éditorial
Publié
Date de publication
1996
Volume
116
Numéro
12
Première page
985
Dernière page/numéro d’article
993
Langue
français
Notes
Publication types: English Abstract ; Journal Article ; ReviewPublication Status: ppublish
Résumé
Nowadays more and more children survive after an intensive anti-tumoral therapy. The price to pay consists of numerous and relatively frequent long-term sequelae (secondary tumors, neuropsychological deficits, endocrine or cardiac damage). After chemotherapy, we sometimes observe renal side-effects, either tubular (metabolic acidosis, hypokalemia, hypomagnesemia, proteinuria, Fanconi syndrome, rickets) or glomerular (acute or chronic decreased GFR). These renal toxic side-effects are encountered especially after cisplatinum and ifosfamide, less frequently after carboplatin and cyclophosphamide. The pediatrician has to be aware of these toxic nephrologic side-effects, to look out for them and monitor carefully the renal function of all paediatric patients receiving these potentially nephrotoxic chemotherapies.
Sujets
PID Serval
serval:BIB_1D067B31B465
PMID
Date de création
2013-04-24T09:27:57.974Z
Date de création dans IRIS
2025-05-20T13:24:03Z