Titre
Hémodynamique cérébrale et hypertensions intracrâniennes [Cerebral hemodynamics and intracranial hypertension]
Type
synthèse (review)
Institution
UNIL/CHUV/Unisanté + institutions partenaires
Auteur(s)
Bracco, D.
Auteure/Auteur
Bissonnette, B.
Auteure/Auteur
Favre, J.B.
Auteure/Auteur
Moeschler, O.
Auteure/Auteur
Boulard, G.
Auteure/Auteur
Ravussin, P.
Auteure/Auteur
Liens vers les personnes
Liens vers les unités
ISSN
0750-7658
Statut éditorial
Publié
Date de publication
1997
Volume
16
Numéro
4
Première page
429
Dernière page/numéro d’article
434
Peer-reviewed
Oui
Langue
français
Notes
Publication types: English Abstract ; Journal Article ; Review
Résumé
Various cerebral aggressions, either primary or secondary, can lead to the development of raised intracranial pressure. The presence of an elevated intracranial pressure often results in cerebral ischaemia/hypoxia and, eventually, neuronal death. In face of this cascade of events, several therapeutic approaches have been suggested. Two management concepts for patients with raised intracranial pressure have retained the most attention in recent years: the first suggests a therapeutic increase in cerebral perfusion pressure with the objectives to improve perilesional collateral perfusion and decreased cerebral blood volume, and consequently intracranial pressure in areas where autoregulation is preserved. The second concept supports the diminution in perilesional capillary pressure with the aim of decreasing vasogenic oedema. Although these two concepts are antagonistic and cannot be used simultaneously, they are probably complementary in the sequence of therapeutic events of patients experiencing severe head injury. This article reviews these therapeutic concepts and their clinical applications.
Sujets
PID Serval
serval:BIB_EAB4597B9F4D
PMID
Date de création
2008-01-17T15:20:14.761Z
Date de création dans IRIS
2025-05-21T05:35:09Z