Titre
Accuracy of preoperative staging for a priori resectable esophageal cancer.
Type
article
Institution
UNIL/CHUV/Unisanté + institutions partenaires
Périodique
Auteur(s)
Winiker, M.
Auteure/Auteur
Mantziari, S.
Auteure/Auteur
Figueiredo, S.G.
Auteure/Auteur
Demartines, N.
Auteure/Auteur
Allemann, P.
Auteure/Auteur
Schäfer, M.
Auteure/Auteur
Liens vers les personnes
Liens vers les unités
ISSN
1442-2050
Statut éditorial
Publié
Date de publication
2018-01-01
Volume
31
Numéro
1
Première page
1
Dernière page/numéro d’article
6
Peer-reviewed
Oui
Langue
anglais
Notes
Publication types: Journal Article
Publication Status: ppublish
Publication Status: ppublish
Résumé
This study assessed the accuracy of preoperative staging in patients undergoing oncological esophagectomy for adenocarcinoma and squamous cell carcinoma. All patients undergoing surgery for resectable esophageal cancer in a university hospital from 2005 to 2016 were identified from our institutional database. Patients with neoadjuvant treatment were excluded to avoid bias from down-staging effects. Routinely, all patients had an upper endoscopy with biopsy, a thoracoabdominal CT scan, an 18-FEG PET-CT, and endoscopic ultrasound. Preoperative staging was compared to histopathological staging of surgical specimen that was considered as gold standard. There were 51 patients with a median age of 65 years (IQR: 59.3-73 years) having 21 squamous cell carcinoma and 30 adenocarcinoma, respectively. T- and N-stages were correctly predicted in 26 (51%) and 37 patients (72%), respectively. Overall, 18 patients (35%) were preoperatively diagnosed with a correct T- and N-stage. There was no difference between adenocarcinoma and squamous cell carcinoma. Accuracy of the T-stage was not influenced by the smoking status. The N-stage was not correct in 7/22 smoking patients (32%) and 6/29 nonsmoking patients (21%).The N-stage was underestimated in smoking patients as 6/22 patients (27%) had a histologically confirmed N+ who were preoperatively classified as N0. In conclusion, only 35% of patients had a correct assessment. Separate T- and N-stage prediction was improved with 51% and 72%, respectively. Major efforts are needed for improvement.
PID Serval
serval:BIB_E41150624ED7
PMID
Open Access
Oui
Date de création
2018-01-27T12:19:44.599Z
Date de création dans IRIS
2025-05-21T05:52:48Z
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Nom
dox113.pdf
Version du manuscrit
published
Taille
430.93 KB
Format
Adobe PDF
PID Serval
serval:BIB_E41150624ED7.P001
URN
urn:nbn:ch:serval-BIB_E41150624ED76
Somme de contrôle
(MD5):e30b30d79c4fb8ea7367b03f8a10d86f