Titre
Anomalies du transport rénal du sodium et sensibilité au sel de la pression artérielle [Abnormalities of renal sodium transport and blood pressure sensitivity to salt].
Type
synthèse (review)
Institution
Externe
Périodique
Auteur(s)
Burnier, M.
Auteure/Auteur
Liens vers les personnes
ISSN
1769-7255
Statut éditorial
Publié
Date de publication
2007
Volume
3 Suppl 2
Numéro
Suppl. 2
Première page
S94
Dernière page/numéro d’article
S98
Peer-reviewed
Oui
Langue
français
Notes
Publication types: English Abstract ; Journal Article
Publication Status: ppublish
Publication Status: ppublish
Résumé
The blood pressure response to changes in dietary salt intake is highly variable among individuals and this heterogeneity results from the combined effects of genetic and environmental factors. In recent years, considerable progress has been made in our understanding of the pathogenic mechanisms leading to the development of salt-sensitive hypertension. Much information has come from the investigation of rare monogenic forms of salt-sensitive hypertension and has focused the attention on alterations of renal sodium handling occurring essentially in the distal segments of the nephron. There is now also extending experimental, clinical, genetic and epidemiological evidence suggesting that proximal tubular function is an important determinant of the blood pressure response to salt that would deserve a greater attention.
PID Serval
serval:BIB_B8DE0612E09D
PMID
Date de création
2008-03-06T10:33:29.116Z
Date de création dans IRIS
2025-05-21T03:59:49Z