Titre
Risk of Recurrence and Surgery after a First Episode of Uncomplicated left- sided Diverticulitis. A Decade of follow- up
Type
mémoire de master/maîtrise/licence
Institution
UNIL/CHUV/Unisanté + institutions partenaires
Auteur(s)
CARLETTA, D.
Auteure/Auteur
Directrices/directeurs
CHRISTOFORIDIS, D.
Directeur⸱rice
POPESKOU, S.
Codirecteur⸱rice
Liens vers les personnes
Liens vers les unités
Faculté
Université de Lausanne, Faculté de biologie et médecine
Statut éditorial
Accepté
Date de publication
2023
Nombre de pages
18
Langue
anglais
Résumé
Background: Acute diverticulitis of the left colon is common and mostly benign. Due to controversy in staging
systems and lack of adequate follow-up in most studies, good quality data to predict long term outcomes after
a first episode of uncomplicated diverticulitis are missing. The aim of this study, was to assess the long-term
risk for adverse outcomes after a first episode of uncomplicated diverticulitis.
Methods: All consecutive patients with a CT-scan documented first episode of acute uncomplicated
diverticulitis between January 2010 and June 2013 were included in the study. CT-scans and clinical records
were retrospectively reviewed. The primary endpoint was overall recurrence, secondary endpoint was surgery
for diverticular disease.
Results: One-hundred-five patients were included in the study with a median follow-up of 116.4 (4.9-154.7)
months. Of these, 51 (48.5%) patients had a recurrence, 11 (10.4%) had 4 or more episodes. Twenty-one (20%)
patients underwent sigmoidectomy, all in an elective setting, mostly due to multiple recurrent episodes. Upon
both univariate and multivariate analyses, male gender was identified as the only risk factor for surgery
(p=0.021).
Conclusion: After a decade of follow-up, one out of two patients will have experienced recurrence after a first
episode of uncomplicated diverticulitis. None of those patients required emergency surgery, but one out of 5,
mostly men, underwent elective sigmoidectomy for multiple recurrent episodes.
systems and lack of adequate follow-up in most studies, good quality data to predict long term outcomes after
a first episode of uncomplicated diverticulitis are missing. The aim of this study, was to assess the long-term
risk for adverse outcomes after a first episode of uncomplicated diverticulitis.
Methods: All consecutive patients with a CT-scan documented first episode of acute uncomplicated
diverticulitis between January 2010 and June 2013 were included in the study. CT-scans and clinical records
were retrospectively reviewed. The primary endpoint was overall recurrence, secondary endpoint was surgery
for diverticular disease.
Results: One-hundred-five patients were included in the study with a median follow-up of 116.4 (4.9-154.7)
months. Of these, 51 (48.5%) patients had a recurrence, 11 (10.4%) had 4 or more episodes. Twenty-one (20%)
patients underwent sigmoidectomy, all in an elective setting, mostly due to multiple recurrent episodes. Upon
both univariate and multivariate analyses, male gender was identified as the only risk factor for surgery
(p=0.021).
Conclusion: After a decade of follow-up, one out of two patients will have experienced recurrence after a first
episode of uncomplicated diverticulitis. None of those patients required emergency surgery, but one out of 5,
mostly men, underwent elective sigmoidectomy for multiple recurrent episodes.
PID Serval
serval:BIB_B517F51AF16C
Date de création
2024-08-12T12:55:09.077Z
Date de création dans IRIS
2025-05-21T02:55:15Z
Fichier(s)![Vignette d'image]()
En cours de chargement...
Nom
Mémoire no 10068 M. Carletta.pdf
Version du manuscrit
imprimatur
Taille
379.05 KB
Format
Adobe PDF
PID Serval
serval:BIB_B517F51AF16C.P001
Somme de contrôle
(MD5):5c161f7f9fa5a9d19f37c3a475ccf3ed