Titre
Phytotherapies, Aliquamments, and Biologicals for the Treatment of Chronic Ulcers : An Introduction
Type
mémoire de master/maîtrise/licence
Institution
UNIL/CHUV/Unisanté + institutions partenaires
Auteur(s)
MARENDAT, L.
Auteure/Auteur
Directrices/directeurs
LAURENT-APPLEGATE, L.
Directeur⸱rice
HIRT-BURRI, N.
Codirecteur⸱rice
Liens vers les personnes
Liens vers les unités
Faculté
Université de Lausanne, Faculté de biologie et médecine
Statut éditorial
Accepté
Date de publication
2024
Nombre de pages
40
Langue
anglais
Résumé
A chronic ulcer is defined as a skin lesion characterised by a loss of tissue substance that persists for a period exceeding three months. These lesions are manifested by continuous destruction of the epidermal and dermal layers, leading to prolonged inflammation and impaired tissue repair processes. They present a considerable challenge to global public health. The Wound Healing Society (nonprofit organization based in the USA composed of clinical and basic scientists and wound care specialists) classifies these ulcers into four main categories: pressure ulcers, diabetic ulcers, venous ulcers, and arterial insufficiency ulcers (which can be mixed). In Switzerland, approximately 1% of the population is affected by leg ulcers, with the prevalence increasing up to 3% among individuals over the age of 65 and the prevalence increases in direct proportion to the aging population. The prevalence can be further compounded by the presence of comorbidities such as vascular insufficiency, diabetes, cancer, and malnutrition. These wounds have been demonstrated to significantly impair patients’ quality-of-life, while simultaneously imposing a significant economic burden on the healthcare system augmenting costs associated with prolonged treatment and care that such wounds require.
Traditional wound management techniques that have been in use for millennia offer potential alternatives to the modern wound dressings which are often expensive and inaccessible in developing countries. Natural remedies, including plant extracts, honey, and larvae, have been demonstrated to exhibit therapeutic properties such as antimicrobial, anti-inflammatory, and cell-stimulating effects. Consequently, they represent a promising avenue for the treatment of chronic wounds.
The study herein aims to review the existing literature on chronic ulcer treatments, with a focus on the feasibility and practicality of these methods in under-resourced geographical regions and environments. The study employs a bibliographic search across various databases and selects relevant articles from 2005 to 2024.
The results demonstrate significant regional disparities in the management of chronic ulcers World-wide. In regions such as Africa, Southeast Asia, and South America, traditional medicine is prevalent due to cultural practices, economic constraints, and limited access to conventional healthcare. Conversely, Europe exhibits a predilection for conventional medicine, supported by well-developed healthcare systems and rigorous regulations on alternative treatments.
The study examines a range of traditional and complementary medicine (T&CM) approaches, including the use of banana leaves, aloe vera, herbal oils, and maggot therapy. These methods, while offering cost-effective solutions, face challenges related to standardization, clinical validation, and integration into modern medical protocols. It is argued that there is a need for policies that would support the integration of validated traditional practices into national health systems. In addition, it is highlighted that there is a need for collaboration between traditional healers, researchers, and healthcare professionals.
In summary, it is argued that a comprehensive approach to chronic wound care is required, taking into consideration technical, economic, and socio-cultural aspects. The integration of T&CM into contemporary healthcare systems addresses medical needs while also aligning with cultural and economic realities, providing diverse and accessible treatment options. This study recommends the development of standardized wound treatment protocols that utilize locally available resources, thereby improving accessibility and reducing healthcare costs in developing regions.
Traditional wound management techniques that have been in use for millennia offer potential alternatives to the modern wound dressings which are often expensive and inaccessible in developing countries. Natural remedies, including plant extracts, honey, and larvae, have been demonstrated to exhibit therapeutic properties such as antimicrobial, anti-inflammatory, and cell-stimulating effects. Consequently, they represent a promising avenue for the treatment of chronic wounds.
The study herein aims to review the existing literature on chronic ulcer treatments, with a focus on the feasibility and practicality of these methods in under-resourced geographical regions and environments. The study employs a bibliographic search across various databases and selects relevant articles from 2005 to 2024.
The results demonstrate significant regional disparities in the management of chronic ulcers World-wide. In regions such as Africa, Southeast Asia, and South America, traditional medicine is prevalent due to cultural practices, economic constraints, and limited access to conventional healthcare. Conversely, Europe exhibits a predilection for conventional medicine, supported by well-developed healthcare systems and rigorous regulations on alternative treatments.
The study examines a range of traditional and complementary medicine (T&CM) approaches, including the use of banana leaves, aloe vera, herbal oils, and maggot therapy. These methods, while offering cost-effective solutions, face challenges related to standardization, clinical validation, and integration into modern medical protocols. It is argued that there is a need for policies that would support the integration of validated traditional practices into national health systems. In addition, it is highlighted that there is a need for collaboration between traditional healers, researchers, and healthcare professionals.
In summary, it is argued that a comprehensive approach to chronic wound care is required, taking into consideration technical, economic, and socio-cultural aspects. The integration of T&CM into contemporary healthcare systems addresses medical needs while also aligning with cultural and economic realities, providing diverse and accessible treatment options. This study recommends the development of standardized wound treatment protocols that utilize locally available resources, thereby improving accessibility and reducing healthcare costs in developing regions.
PID Serval
serval:BIB_218ED68BB592
Date de création
2024-09-02T07:25:17.201Z
Date de création dans IRIS
2025-05-20T18:44:42Z
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Nom
Mémoire no 10844 Mme Marendat Lauranne.pdf
Version du manuscrit
imprimatur
Taille
6.77 MB
Format
Adobe PDF
PID Serval
serval:BIB_218ED68BB592.P001
Somme de contrôle
(MD5):3cadd8dbd841cb5be3fa984ba2cc3254