Titre
Physiopathologie de l’hypoxémie silencieuse dans le Covid-19 [Pathophysiology of COVID-19 related happy hypoxemia]
Type
article
Institution
UNIL/CHUV/Unisanté + institutions partenaires
Périodique
Auteur(s)
Breville, G.
Auteure/Auteur
Accorroni, A.
Auteure/Auteur
Allali, G.
Auteure/Auteur
Adler, D.
Auteure/Auteur
Liens vers les personnes
Liens vers les unités
ISSN
1660-9379
Statut éditorial
Publié
Date de publication
2021-04-28
Volume
17
Numéro
736
Première page
831
Dernière page/numéro d’article
834
Peer-reviewed
Oui
Langue
français
Notes
Publication types: Journal Article
Publication Status: ppublish
Publication Status: ppublish
Résumé
A significative proportion of patients with pulmonary-related COVID-19 initially present with « silent » or « happy » hypoxemia, a term denoting an absence of dyspnea or other respiratory distress symptoms in face of profound hypoxemia. COVID-19 is a multisystemic disease characterized by the diffusion of SARS-COV-2 through the blood and a widespread secondary immune response. Most of the organs are involved, including the brain and this translates into the development of acute encephalopathy and other complications. Silent hypoxemia and the consequent "vanishing dyspnea" represent a loss of warning signal and may be associated with a rapid clinical worsening and a fatal outcome. In this article, we will describe the physiological basis of ventilation and we will elucidate the different pathophysiological mechanisms underlying the phenomenon of silent hypoxemia in COVID-19.
PID Serval
serval:BIB_4C1A6977B265
PMID
Date de création
2023-10-04T20:28:02.581Z
Date de création dans IRIS
2025-05-20T16:05:42Z
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Nom
33908720.pdf
Version du manuscrit
published
Licence
https://creativecommons.org/licenses/by-nc-nd/4.0
Taille
459.92 KB
Format
Adobe PDF
PID Serval
serval:BIB_4C1A6977B265.P001
URN
urn:nbn:ch:serval-BIB_4C1A6977B2657
Somme de contrôle
(MD5):02ee6df77eebefa925521c23b01c739c