Titre
Endoscopic subureteral collagen injection for the treatment of vesicoureteral reflux in infants and children.
Type
article
Institution
UNIL/CHUV/Unisanté + institutions partenaires
Périodique
Auteur(s)
Frey, P.
Auteure/Auteur
Lutz, N.
Auteure/Auteur
Jenny, P.
Auteure/Auteur
Herzog, B.
Auteure/Auteur
Liens vers les personnes
Liens vers les unités
ISSN
0022-5347
Statut éditorial
Publié
Date de publication
1995-08
Volume
154
Numéro
2 Pt 2
Première page
804
Dernière page/numéro d’article
807
Peer-reviewed
Oui
Langue
anglais
Notes
Publication types: Clinical Trial ; Journal Article ; Research Support, Non-U.S. Gov't
Publication Status: ppublish
Publication Status: ppublish
Résumé
Between June 1988 and September 1994, 100 girls and 32 boys 2 months to 15.5 years old (average 4.9 years) with 204 refluxing ureteral units were treated by endoscopic subureteral collagen injection. The collagen injected was of bovine origin and cross-linked with glutaraldehyde (Zyplast*). Followup ranged from 3 to 75 months (mean 33). Reflux was absent in 62.7% of cases 3 months after 1 endoscopic subureteral injection. Improvement to reflux grades I and II, generally not requiring further treatment, occurred in a further 15.2% of cases. A total of 66 ureters was injected twice. The overall cure rate after 1 or 2 injections was 79.4% 3 months after injection. There was no correlation between the risk of recurrent reflux and initial degree of reflux. Late recurrence of reflux following a reflux-free period occurred in 11.3% of the 204 units during the observation period, which varied from 3 months to 6 1/4 years. Reflux was absent after 1 or 2 injections, including late recurrence, in 70.6% of cases and in an additional 13.2% recurrent reflux was grade I or II, not necessitating any further treatment. Considering these results, subureteral collagen injection remains an adequate method of treatment for vesicoureteral reflux in children.
PID Serval
serval:BIB_560E2BAB1085
PMID
Date de création
2008-02-28T09:25:15.882Z
Date de création dans IRIS
2025-05-20T15:32:53Z