Titre
European Prevention of Alzheimer's Dementia Registry: Recruitment and prescreening approach for a longitudinal cohort and prevention trials.
Type
article
Institution
UNIL/CHUV/Unisanté + institutions partenaires
Auteur(s)
Vermunt, L.
Auteure/Auteur
Veal, C.D.
Auteure/Auteur
Ter Meulen, L.
Auteure/Auteur
Chrysostomou, C.
Auteure/Auteur
van der Flier, W.
Auteure/Auteur
Frisoni, G.B.
Auteure/Auteur
Guessous, I.
Auteure/Auteur
Kivipelto, M.
Auteure/Auteur
Marizzoni, M.
Auteure/Auteur
Martinez-Lage, P.
Auteure/Auteur
Molinuevo, J.L.
Auteure/Auteur
Porteous, D.
Auteure/Auteur
Ritchie, K.
Auteure/Auteur
Scheltens, P.
Auteure/Auteur
Ousset, P.J.
Auteure/Auteur
Ritchie, C.W.
Auteure/Auteur
Luscan, G.
Auteure/Auteur
Brookes, A.J.
Auteure/Auteur
Visser, P.J.
Auteure/Auteur
Liens vers les personnes
Liens vers les unités
ISSN
1552-5279
Statut éditorial
Publié
Date de publication
2018-06
Volume
14
Numéro
6
Première page
837
Dernière page/numéro d’article
842
Peer-reviewed
Oui
Langue
anglais
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't
Publication Status: ppublish
Publication Status: ppublish
Résumé
It is a challenge to find participants for Alzheimer's disease (AD) prevention trials within a short period of time. The European Prevention of Alzheimer's Dementia Registry (EPAD) aims to facilitate recruitment by preselecting subjects from ongoing cohort studies. This article introduces this novel approach.
A virtual registry, with access to risk factors and biomarkers for AD through minimal data sets of ongoing cohort studies, was set up.
To date, ten cohorts have been included in the EPAD. Around 2500 participants have been selected, using variables associated with the risk for AD. Of these, 15% were already recruited in the EPAD longitudinal cohort study, which serves as a trial readiness cohort.
This study demonstrates that a virtual registry can be used for the preselection of participants for AD studies.
A virtual registry, with access to risk factors and biomarkers for AD through minimal data sets of ongoing cohort studies, was set up.
To date, ten cohorts have been included in the EPAD. Around 2500 participants have been selected, using variables associated with the risk for AD. Of these, 15% were already recruited in the EPAD longitudinal cohort study, which serves as a trial readiness cohort.
This study demonstrates that a virtual registry can be used for the preselection of participants for AD studies.
PID Serval
serval:BIB_E0E608EAD1EF
PMID
Date de création
2018-04-12T16:07:39.654Z
Date de création dans IRIS
2025-05-20T22:52:03Z