Titre
Elements of olfactory reception in adult Drosophila melanogaster.
Type
article
Institution
UNIL/CHUV/Unisanté + institutions partenaires
Auteur(s)
Martin, F.
Auteure/Auteur
Boto, T.
Auteure/Auteur
Gomez-Diaz, C.
Auteure/Auteur
Alcorta, E.
Auteure/Auteur
Liens vers les personnes
Liens vers les unités
ISSN
1932-8494
Statut éditorial
Publié
Date de publication
2013
Volume
296
Numéro
9
Première page
1477
Dernière page/numéro d’article
1488
Langue
anglais
Résumé
The olfactory system of Drosophila has become an attractive and simple model to investigate olfaction because it follows the same organizational principles of vertebrates, and the results can be directly applied to other insects with economic and sanitary relevance. Here, we review the structural elements of the Drosophila olfactory reception organs at the level of the cells and molecules involved. This article is intended to reflect the structural basis underlying the functional variability of the detection of an olfactory universe composed of thousands of odors. At the genetic level, we further detail the genes and transcription factors (TF) that determine the structural variability. The fly's olfactory receptor organs are the third antennal segments and the maxillary palps, which are covered with sensory hairs called sensilla. These sensilla house the odorant receptor neurons (ORNs) that express one or few odorant receptors in a stereotyped pattern regulated by combinations of TF. Also, perireceptor events, such as odor molecules transport to their receptors, are carried out by odorant binding proteins. In addition, the rapid odorant inactivation to preclude saturation of the system occurs by biotransformation and detoxification enzymes. These additional events take place in the lymph that surrounds the ORNs. We include some data on ionotropic and metabotropic olfactory transduction, although this issue is still under debate in Drosophila.
PID Serval
serval:BIB_6A2A0EE10329
PMID
Open Access
Oui
Date de création
2013-11-14T08:58:18.986Z
Date de création dans IRIS
2025-05-21T01:30:59Z