Titre
Natural and synthetic nanovectors for cancer therapy.
Type
synthèse (review)
Institution
UNIL/CHUV/Unisanté + institutions partenaires
Périodique
Nanotheranostics
Auteur(s)
Eftekhari, A.
Auteure/Auteur
Kryschi, C.
Auteure/Auteur
Pamies, D.
Auteure/Auteur
Gulec, S.
Auteure/Auteur
Ahmadian, E.
Auteure/Auteur
Janas, D.
Auteure/Auteur
Davaran, S.
Auteure/Auteur
Khalilov, R.
Auteure/Auteur
Liens vers les personnes
Liens vers les unités
ISSN
2206-7418
Statut éditorial
Publié
Date de publication
2023
Volume
7
Numéro
3
Première page
236
Dernière page/numéro d’article
257
Peer-reviewed
Oui
Langue
anglais
Notes
Publication types: Journal Article ; Review ; Research Support, Non-U.S. Gov't
Publication Status: epublish
Publication Status: epublish
Résumé
Nanomaterials have been extensively studied in cancer therapy as vectors that may improve drug delivery. Such vectors not only bring numerous advantages such as stability, biocompatibility, and cellular uptake but have also been shown to overcome some cancer-related resistances. Nanocarrier can deliver the drug more precisely to the specific organ while improving its pharmacokinetics, thereby avoiding secondary adverse effects on the not target tissue. Between these nanovectors, diverse material types can be discerned, such as liposomes, dendrimers, carbon nanostructures, nanoparticles, nanowires, etc., each of which offers different opportunities for cancer therapy. In this review, a broad spectrum of nanovectors is analyzed for application in multimodal cancer therapy and diagnostics in terms of mode of action and pharmacokinetics. Advantages and inconveniences of promising nanovectors, including gold nanostructures, SPIONs, semiconducting quantum dots, various nanostructures, phospholipid-based liposomes, dendrimers, polymeric micelles, extracellular and exome vesicles are summarized. The article is concluded with a future outlook on this promising field.
PID Serval
serval:BIB_1413AD195F3E
PMID
Open Access
Oui
Date de création
2023-04-25T12:37:53.166Z
Date de création dans IRIS
2025-05-20T18:32:56Z
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Nom
37064613_BIB_1413AD195F3E.pdf
Version du manuscrit
preprint
Licence
https://creativecommons.org/licenses/by/4.0
Taille
4.78 MB
Format
Adobe PDF
PID Serval
serval:BIB_1413AD195F3E.P001
URN
urn:nbn:ch:serval-BIB_1413AD195F3E3
Somme de contrôle
(MD5):8d6b351a2302351bb89adc4a006804a6