Titre
Inflammation, anxiety, and stress in bipolar disorder and borderline personality disorder: A narrative review.
Type
synthèse (review)
Institution
UNIL/CHUV/Unisanté + institutions partenaires
Périodique
Auteur(s)
Saccaro, L.F.
Auteure/Auteur
Schilliger, Z.
Auteure/Auteur
Dayer, A.
Auteure/Auteur
Perroud, N.
Auteure/Auteur
Piguet, C.
Auteure/Auteur
Liens vers les personnes
Liens vers les unités
ISSN
1873-7528
Statut éditorial
Publié
Date de publication
2021-08
Volume
127
Première page
184
Dernière page/numéro d’article
192
Peer-reviewed
Oui
Langue
anglais
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't ; Review
Publication Status: ppublish
Publication Status: ppublish
Résumé
Bipolar disorder (BD) and borderline personality disorder (BPD) are serious and prevalent psychiatric diseases that share common phenomenological characteristics: symptoms (such as anxiety, affective lability or emotion dysregulation), neuroimaging features, risk factors and comorbidities. While several studies have focused on the link between stress and peripheral inflammation in other affective disorders such as anxiety or depression, fewer have explored this relationship in BD and BPD. This review reports on evidence showing an interplay between immune dysregulation, anxiety and stress, and how an altered acute neuroendocrine stress response may exist in these disorders. Moreover, we highlight limitations and confounding factors of these existing studies and discuss multidirectional hypotheses that either suggest inflammation or stress and anxiety as the primum movens in BD and BPD pathophysiology, or inflammation as a consequence of the pathophysiology of these diseases. Untangling these associations and implementing a transdiagnostic approach will have diagnostic, therapeutic and prognostic implications for BD and BPD patients.
PID Serval
serval:BIB_3A0BA151DCAF
PMID
Open Access
Oui
Date de création
2021-05-19T11:33:45.135Z
Date de création dans IRIS
2025-05-20T16:28:35Z
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Nom
Inflammation, anxiety, and stress in bipolar disorder and borderline personality disorder.pdf
Version du manuscrit
published
Licence
https://creativecommons.org/licenses/by-nc-nd/4.0
Taille
2.12 MB
Format
Adobe PDF
PID Serval
serval:BIB_3A0BA151DCAF.P001
URN
urn:nbn:ch:serval-BIB_3A0BA151DCAF7
Somme de contrôle
(MD5):4c4735991dbe2b2e9d19ed0af33f6393