Titre
L'initiation du traitement dans la maladie de Parkinson [Initiation of treatment in Parkinson disease].
Type
article
Institution
UNIL/CHUV/Unisanté + institutions partenaires
Périodique
Auteur(s)
Ghika, J.
Auteure/Auteur
Liens vers les personnes
Liens vers les unités
ISSN
1661-8157
Statut éditorial
Publié
Date de publication
1995
Volume
84
Numéro
38
Première page
1018
Dernière page/numéro d’article
1020
Langue
français
Notes
Publication types: English Abstract ; Journal Article
Publication Status: ppublish
Publication Status: ppublish
Résumé
Initiating treatment in a patient with Parkinson's disease requires consideration of age, degree of disease activity, and consequences of long-term treatment. In young patients, albeit dopaminergic agonists or selegiline are possible alternatives, they will never be as effective as L-dopa, and they can be used only initially in very mild cases and for a short period of time. Long-acting L-dopa is probably better after titration with standard preparations. Potential neuroprotection by selegiline has not been confirmed so far, but it acts as a mild anti-Parkinsonian. In patients over 60, it is recommended not to use anticholinergic or dopaminergic agonists, but to start with a low dose of L-dopa and increase it by a maximum of 125 mg every 7 to 10 days. Clozapine can be very useful against psychosis.
PID Serval
serval:BIB_3FBB9284EA34
PMID
Date de création
2008-01-25T10:45:42.186Z
Date de création dans IRIS
2025-05-20T14:06:14Z