Titre
Ipsilateral blepharospasm and contralateral hemidystonia and parkinsonism in a patient with a unilateral rostral brainstem-thalamic lesion: structural and functional abnormalities studied with CT, MRI, and PET scanning.
Type
étude de cas
Institution
Externe
Périodique
Auteur(s)
Leenders, K.L.
Auteure/Auteur
Frackowiak, R.S.
Auteure/Auteur
Quinn, N.
Auteure/Auteur
Brooks, D.
Auteure/Auteur
Sumner, D.
Auteure/Auteur
Marsden, C.D.
Auteure/Auteur
Liens vers les personnes
ISSN
0885-3185
Statut éditorial
Publié
Date de publication
1986
Volume
1
Numéro
1
Première page
51
Dernière page/numéro d’article
58
Langue
anglais
Notes
Publication types: Case Reports ; Journal ArticlePublication Status: ppublish
Résumé
A patient developed progressive right hemidystonia in childhood. Subsequently, left-sided blepharospasm, slurred and stuttering speech, and right-sided rigidity and bradykinesia, responsive to dopamine agonists, appeared. Investigation with computed tomography and magnetic resonance imaging (MRI) at age 43 years revealed a left-sided calcified rostral brainstem-thalamic lesion of uncertain aetiology. Although no structural lesion was seen in the striatal regions, L-[18F]-fluorodopa uptake was severely diminished in the left striatum but normal on the right. Dopamine receptor binding identified by [11C]-methylspiperone was in the normal range on both sides.
PID Serval
serval:BIB_C4246F4D43A2
PMID
Date de création
2011-10-09T16:25:42.676Z
Date de création dans IRIS
2025-05-20T22:47:14Z