Titre
Access, autonomy, and affordability: ethical and human rights issues surrounding multigene panel testing for cancer in Japan and Switzerland.
Type
article
Institution
UNIL/CHUV/Unisanté + institutions partenaires
Périodique
Auteur(s)
Nakasato, K.
Auteure/Auteur
Manz, C.
Auteure/Auteur
Kato, K.
Auteure/Auteur
Liens vers les personnes
Liens vers les unités
ISSN
1664-8021
Statut éditorial
Publié
Date de publication
2024
Volume
15
Première page
1343720
Peer-reviewed
Oui
Langue
anglais
Notes
Publication types: Journal Article
Publication Status: epublish
Publication Status: epublish
Résumé
Introduction: Advancements in precision medicine and genomics have led to prospects in a wide range of clinical fields, including oncology. In particular, developments in next-generation sequencing multigene panel tests have led to the possibility of tailoring treatment to the specific genomic markers of a patient's cancer. However, findings from current literature suggest that the path to implementation and uptake of genomic medicine is not without uncertainties and challenges. Methods: To better understand the current challenges to the implementation of genomic medicine services, we investigated the current state of patient access to genomic medicine in Japan and Switzerland. In this investigation, we focused on equal access, patient autonomy, and healthcare affordability. Results: Results have shown that although multigene panel testing is in principle covered by health insurance in both countries, barriers exist in terms of where the tests are available, comprehensive information for patients, and the affordability of not only the test itself but the overall process from diagnosis to treatment. Discussion: These results suggest a need to continue examining a more diverse range of clinical landscapes for genomic medicine to reveal more nuanced understandings of barriers to implementation and thus better identify best practices for overcoming them.
PID Serval
serval:BIB_8E6A74501D12
PMID
Open Access
Oui
Date de création
2024-02-20T14:08:36.183Z
Date de création dans IRIS
2025-05-21T02:42:36Z
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Nom
38343692_BIB_8E6A74501D12.pdf
Version du manuscrit
published
Licence
https://creativecommons.org/licenses/by/4.0
Taille
665.56 KB
Format
Adobe PDF
PID Serval
serval:BIB_8E6A74501D12.P001
URN
urn:nbn:ch:serval-BIB_8E6A74501D126
Somme de contrôle
(MD5):d5dc6b6922b9a82f1609432bfefa3b79