Titre
Homoeologs: What Are They and How Do We Infer Them?
Type
synthèse (review)
Institution
UNIL/CHUV/Unisanté + institutions partenaires
Périodique
Auteur(s)
Glover, N.M.
Auteure/Auteur
Redestig, H.
Auteure/Auteur
Dessimoz, C.
Auteure/Auteur
Liens vers les personnes
Liens vers les unités
ISSN
1878-4372
Statut éditorial
Publié
Date de publication
2016
Volume
21
Numéro
7
Première page
609
Dernière page/numéro d’article
621
Peer-reviewed
Oui
Langue
anglais
Résumé
The evolutionary history of nearly all flowering plants includes a polyploidization event. Homologous genes resulting from allopolyploidy are commonly referred to as 'homoeologs', although this term has not always been used precisely or consistently in the literature. With several allopolyploid genome sequencing projects under way, there is a pressing need for computational methods for homoeology inference. Here we review the definition of homoeology in historical and modern contexts and propose a precise and testable definition highlighting the connection between homoeologs and orthologs. In the second part, we survey experimental and computational methods of homoeolog inference, considering the strengths and limitations of each approach. Establishing a precise and evolutionarily meaningful definition of homoeology is essential for understanding the evolutionary consequences of polyploidization.
PID Serval
serval:BIB_59A0CA77B84B
PMID
Open Access
Oui
Date de création
2016-04-09T14:10:41.744Z
Date de création dans IRIS
2025-05-20T18:37:08Z
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Nom
BIB_59A0CA77B84B.P001.pdf
Version du manuscrit
published
Taille
1.68 MB
Format
Adobe PDF
PID Serval
serval:BIB_59A0CA77B84B.P001
URN
urn:nbn:ch:serval-BIB_59A0CA77B84B4
Somme de contrôle
(MD5):fa9e68d328f0c84d0aa6441739b3e925