Titre
Diuretics in pediatrics.
Type
synthèse (review)
Institution
UNIL/CHUV/Unisanté + institutions partenaires
Périodique
Auteur(s)
Lava, SAG
Auteure/Auteur
Zollinger, C.
Auteure/Auteur
Chehade, H.
Auteure/Auteur
Schaffner, D.
Auteure/Auteur
Sekarski, N.
Auteure/Auteur
Di Bernardo, S.
Auteure/Auteur
Liens vers les personnes
Liens vers les unités
ISSN
1432-1076
Statut éditorial
Publié
Date de publication
2023-05
Volume
182
Numéro
5
Première page
2077
Dernière page/numéro d’article
2088
Peer-reviewed
Oui
Langue
anglais
Notes
Publication types: Journal Article ; Review
Publication Status: ppublish
Publication Status: ppublish
Résumé
Diuretics are frequently prescribed drugs and help managing several pathological conditions, including acute and chronic kidney disease, nephrotic syndrome, congestive heart failure, ascites, systemic and pulmonary hypertension. Diuretic classes include among others osmotic diuretics and carboanhydrase inhibitors, loop diuretics, thiazides, and potassium-sparing diuretics. In this educational article, we aim at reviewing indications, mechanisms of action, and side effects, as well as basic pharmacokinetics considerations and data on diuretics in children, supporting practicing clinicians in choosing (and understanding the background of) the best-suited diuretic regimen for the individual patient. Newer diuretic classes like vaptans and sodium glucose type 2 cotransporter inhibitors, the recent controversies on hydrochlorothiazide, and the issue of diuretic resistance, will also be briefly addressed.
This educational review offers a didactical overview of diuretics in Pediatrics.
• Diuretics are frequently prescribed drugs in both adults and children. • They increase water and sodium excretion, reducing fluid overload.
• This article reviews indications, mechanisms of action, side effects, and basic pharmacokinetics facts on diuretics in Paediatrics. • It also addresses current issues, like the management of diuretic resistance, the recent controversy on hydrochlorothiazide, and the novel classes vaptans and gliflozins.
This educational review offers a didactical overview of diuretics in Pediatrics.
• Diuretics are frequently prescribed drugs in both adults and children. • They increase water and sodium excretion, reducing fluid overload.
• This article reviews indications, mechanisms of action, side effects, and basic pharmacokinetics facts on diuretics in Paediatrics. • It also addresses current issues, like the management of diuretic resistance, the recent controversy on hydrochlorothiazide, and the novel classes vaptans and gliflozins.
PID Serval
serval:BIB_47C8F0997BF2
PMID
Date de création
2022-09-07T13:32:34.591Z
Date de création dans IRIS
2025-05-20T14:42:37Z
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Nom
Mémoire no 8194 Mme Zollinger.pdf
Version du manuscrit
preprint
Taille
1.4 MB
Format
Adobe PDF
PID Serval
serval:BIB_47C8F0997BF2.P001
Somme de contrôle
(MD5):d9ef55b5c38a8dad00c726a998a1d216