Titre
How non-drug interventions affect the quality of life of patients suffering from progressive cognitive decline and their main caregiver.
Type
article
Institution
UNIL/CHUV/Unisanté + institutions partenaires
Périodique
Auteur(s)
Leidi-Maimone, B.
Auteure/Auteur
Notter-Bielser, M.L.
Auteure/Auteur
Laouadi, M.H.
Auteure/Auteur
Perrin, S.
Auteure/Auteur
Métraux, H.
Auteure/Auteur
Damian, D.
Auteure/Auteur
Chavan, C.F.
Auteure/Auteur
Nsir, M.
Auteure/Auteur
Cibelli, G.
Auteure/Auteur
Tâche, M.J.
Auteure/Auteur
Montandon, M.L.
Auteure/Auteur
Ghika, J.
Auteure/Auteur
Démonet, J.F.
Auteure/Auteur
Dürst, A.V.
Auteure/Auteur
Guevara, A.B.
Auteure/Auteur
Liens vers les personnes
Liens vers les unités
ISSN
1945-4589
Statut éditorial
Publié
Date de publication
2020-06-09
Volume
12
Numéro
11
Première page
10754
Dernière page/numéro d’article
10771
Peer-reviewed
Oui
Langue
anglais
Notes
Publication types: Journal Article
Publication Status: ppublish
Publication Status: ppublish
Résumé
In the absence of cure for age-related neurodegenerative diseases, non-drug interventions (NDIs) represent useful options. Quality of life (QOL) is a multidimensional concept progressively affected by cognitive decline. How single or multiple NDIs impact QOL is unknown.
We found no significant effect of multiple over single NDI on QOL. Socio-demographic variables influenced patients' (age, gender, caregivers' occupational status, management of patients' financial affairs) and caregivers' (gender, occupational status, patients' severity of cognitive decline) QOL. When dyads interrupted interventions after 6 months, their QOL was lower and caregivers' anxiety, depression and physical symptoms were higher at the end of the study.
While the type and number of interventions do not appear to be critical, the continuity of adapted interventions in the long-term might be important for maintaining QOL of patients and caregivers.
This is a multicenter (7 Swiss Memory Clinics), quasi-experimental, one-year follow-up study including 148 subjects (mild cognitive impairment or mild dementia patients and their caregivers). Primary outcome was the effect of multiple vs single NDIs on QOL. Secondary outcome included NDIs effect on patients' cognitive impairment and functional autonomy, caregivers' burden, severity of patients' neuropsychiatric symptoms and dyads' anxiety and depression.
We found no significant effect of multiple over single NDI on QOL. Socio-demographic variables influenced patients' (age, gender, caregivers' occupational status, management of patients' financial affairs) and caregivers' (gender, occupational status, patients' severity of cognitive decline) QOL. When dyads interrupted interventions after 6 months, their QOL was lower and caregivers' anxiety, depression and physical symptoms were higher at the end of the study.
While the type and number of interventions do not appear to be critical, the continuity of adapted interventions in the long-term might be important for maintaining QOL of patients and caregivers.
This is a multicenter (7 Swiss Memory Clinics), quasi-experimental, one-year follow-up study including 148 subjects (mild cognitive impairment or mild dementia patients and their caregivers). Primary outcome was the effect of multiple vs single NDIs on QOL. Secondary outcome included NDIs effect on patients' cognitive impairment and functional autonomy, caregivers' burden, severity of patients' neuropsychiatric symptoms and dyads' anxiety and depression.
PID Serval
serval:BIB_4D8137B5A848
PMID
Date de création
2020-06-10T12:21:14.346Z
Date de création dans IRIS
2025-05-20T16:07:03Z
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Nom
32516129_BIB_4D8137B5A848.pdf
Version du manuscrit
published
Licence
https://creativecommons.org/licenses/by/4.0
Taille
1.07 MB
Format
Adobe PDF
PID Serval
serval:BIB_4D8137B5A848.P001
URN
urn:nbn:ch:serval-BIB_4D8137B5A8483
Somme de contrôle
(MD5):5b496deffbf8f7ab42b3ff21b61c505e