Titre
Rationale and design of the prospective German registry of outcome in patients with severe disorders of consciousness after acute brain injury
Type
article
Institution
Externe
Périodique
Arch Phys Med Rehabil
Auteur(s)
Grill, E.
Auteure/Auteur
Klein, A. M.
Auteure/Auteur
Howell, K.
Auteure/Auteur
Arndt, M.
Auteure/Auteur
Bodrozic, L.
Auteure/Auteur
Herzog, J.
Auteure/Auteur
Jox, R.
Auteure/Auteur
Koenig, E.
Auteure/Auteur
Mansmann, U.
Auteure/Auteur
Muller, F.
Auteure/Auteur
Muller, T.
Auteure/Auteur
Nowak, D.
Auteure/Auteur
Schaupp, M.
Auteure/Auteur
Straube, A.
Auteure/Auteur
Bender, A.
Auteure/Auteur
Liens vers les personnes
ISSN
1532-821X
Statut éditorial
Publié
Date de publication
2013-10
Volume
94
Numéro
10
Première page
1870
Dernière page/numéro d’article
6
Langue
anglais
Notes
Grill, Eva
Klein, Anke-Maria
Howell, Kaitlen
Arndt, Marion
Bodrozic, Lydia
Herzog, Jurgen
Jox, Ralf
Koenig, Eberhardt
Mansmann, Ulrich
Muller, Friedemann
Muller, Thomas
Nowak, Dennis
Schaupp, Matthias
Straube, Andreas
Bender, Andreas
eng
Multicenter Study
Research Support, Non-U.S. Gov't
2013/06/05 06:00
Arch Phys Med Rehabil. 2013 Oct;94(10):1870-6. doi: 10.1016/j.apmr.2012.10.040. Epub 2013 May 31.
Klein, Anke-Maria
Howell, Kaitlen
Arndt, Marion
Bodrozic, Lydia
Herzog, Jurgen
Jox, Ralf
Koenig, Eberhardt
Mansmann, Ulrich
Muller, Friedemann
Muller, Thomas
Nowak, Dennis
Schaupp, Matthias
Straube, Andreas
Bender, Andreas
eng
Multicenter Study
Research Support, Non-U.S. Gov't
2013/06/05 06:00
Arch Phys Med Rehabil. 2013 Oct;94(10):1870-6. doi: 10.1016/j.apmr.2012.10.040. Epub 2013 May 31.
Résumé
OBJECTIVE: To describe the rationale and design of a new patient registry (Koma Outcome von Patienten der Fruhrehabilitation-Register [KOPF-R; Registry for Coma Outcome in Patients Undergoing Acute Rehabilitation]) that has the scope to examine determinants of long-term outcome and functioning of patients with severe disorders of consciousness (DOC). DESIGN: Prospective multicenter neurologic rehabilitation registry. SETTING: Five specialized neurologic rehabilitation facilities. PARTICIPANTS: Patients (N=42) with DOC in vegetative state or minimally conscious state (MCS) as defined by the Coma Recovery Scale-Revised (CRS-R) after brain injury. Patients are being continuously enrolled. The data presented here cover the enrollment period from August 2011 to January 2012. INTERVENTIONS: Not applicable. MAIN OUTCOME MEASURES: CRS-R, FIM, and emergence from MCS. RESULTS: The registry was set up in 5 facilities across the state of Bavaria/Germany with a special expertise in the rehabilitation of acquired brain injury. Inclusion of patients started in August 2011. Measures include sociodemographic and clinical characteristics, course of acute therapy, electrophysiologic measures (evoked potentials, electroencephalogram), neuron-specific enolase, current medication, functioning, cognition, participation, quality of life, quantity and characteristics of rehabilitation therapy, caregiver burden, and attitudes toward end-of-life decisions. Main diagnoses were traumatic brain injury (24%), intracerebral or subarachnoid hemorrhage (31%), and anoxic-ischemic encephalopathy (45%). Mean CRS-R score +/- SD at admission to rehabilitation was 5.9 +/- 3.3, and mean FIM score +/- SD at admission was 18 +/- 0.4. CONCLUSIONS: The KOPF-R aspires to contribute prospective data on prognosis in severe DOC.
Sujets
PID Serval
serval:BIB_24C00DC3D7C2
PMID
Date de création
2017-07-14T08:09:02.311Z
Date de création dans IRIS
2025-05-20T14:22:00Z