Titre
Oral and intestinal Candida colonization in patients undergoing hematopoietic stem-cell transplantation.
Type
article
Institution
Externe
Périodique
Auteur(s)
Zollner-Schwetz, I.
Auteure/Auteur
Auner, H.W.
Auteure/Auteur
Paulitsch, A.
Auteure/Auteur
Buzina, W.
Auteure/Auteur
Staber, P.B.
Auteure/Auteur
Ofner-Kopeinig, P.
Auteure/Auteur
Reisinger, E.C.
Auteure/Auteur
Olschewski, H.
Auteure/Auteur
Krause, R.
Auteure/Auteur
Liens vers les personnes
ISSN
0022-1899
Statut éditorial
Publié
Date de publication
2008-07-01
Volume
198
Numéro
1
Première page
150
Dernière page/numéro d’article
153
Peer-reviewed
Oui
Langue
anglais
Notes
Publication types: Journal Article
Publication Status: ppublish
Publication Status: ppublish
Résumé
We investigated (1) the prevalence and quantity of, as well as risk factors for, orointestinal Candida colonization in patients undergoing hematopoietic stem-cell transplantation (HSCT) and (2) the genetic relatedness of colonizing C. albicans strains. Mouth-wash and stool samples were collected from 77 patients before they underwent HSCT and on days 1, 8, and 15 and were quantitatively cultured. C. albicans isolates were genotyped by microsatellite-marker analysis. The prevalence and quantity of orointestinal Candida colonization varied over time. In 48% (13/27) of multicolonized patients, the same Candida genotype was present in oral and intestinal samples. Oral colonization and decontamination of the gut by vancomycin and paromomycin were risk factors for intestinal Candida colonization.
Sujets
PID Serval
serval:BIB_D3167E12FB97
PMID
Open Access
Oui
Date de création
2024-12-02T15:50:05.478Z
Date de création dans IRIS
2025-05-20T21:51:17Z