Titre
Cell cycle regulators in cancer cell metabolism.
Type
synthèse (review)
Institution
UNIL/CHUV/Unisanté + institutions partenaires
Auteur(s)
Leal-Esteban, L.C.
Auteure/Auteur
Fajas, L.
Auteure/Auteur
Liens vers les personnes
Liens vers les unités
ISSN
1879-260X
Statut éditorial
Publié
Date de publication
2020-05-01
Volume
1866
Numéro
5
Première page
165715
Peer-reviewed
Oui
Langue
anglais
Notes
Publication types: Journal Article ; Review ; Research Support, Non-U.S. Gov't
Publication Status: ppublish
Publication Status: ppublish
Résumé
Cancer proliferation and progression involves altered metabolic pathways as a result of continuous demand for energy and nutrients. In the last years, cell cycle regulators have been involved in the control of metabolic processes, such as glucose and insulin pathways and lipid synthesis, in addition to their canonical function controlling cell cycle progression. Here we describe recent data demonstrating the role of cell cycle regulators in the metabolic control especially in studies performed in cancer models. Moreover, we discuss the importance of these findings in the context of current cancer therapies to provide an overview of the relevance of targeting metabolism using inhibitors of the cell cycle regulation.
PID Serval
serval:BIB_DADB4F066621
PMID
Date de création
2020-02-17T14:34:45.648Z
Date de création dans IRIS
2025-05-21T07:02:47Z