Titre
Cytokines in the neuroendocrine system.
Type
synthèse (review)
Institution
UNIL/CHUV/Unisanté + institutions partenaires
Périodique
Auteur(s)
Gaillard, R.C.
Auteure/Auteur
Liens vers les personnes
rgaillar
Liens vers les unités
ISSN
0883-0185
Statut éditorial
Publié
Date de publication
1998
Volume
17
Numéro
1-4
Première page
181
Dernière page/numéro d’article
216
Peer-reviewed
Oui
Langue
anglais
Notes
Publication types: Journal Article
Résumé
Cytokines are important partners in the bidirectional network interrelating the immune and the neuroendocrine systems. These substances and their specific receptors, initially thought to be exclusively present in the immune system, have recently been shown to be also expressed in the neuroendocrine system. Cytokines can modulate the responses of all endocrine axes by acting at both the central and the peripheral levels. To explain how systemic cytokines may gain access to the brain, several mechanisms have been proposed, including an active transport through the blood-brain barrier, a passage at the circumventricular organ level, as well as a neuronal pathway through the vagal nerve. The immune-neuroendocrine interactions are involved in numerous physiological and pathophysiological conditions and seem to play an important role to maintain homeostasis.
PID Serval
serval:BIB_1F3862435B93
PMID
Date de création
2008-02-15T15:57:52.822Z
Date de création dans IRIS
2025-05-20T13:56:57Z