Titre
Venous thromboembolism after esophagectomy for cancer: a systematic review of the literature to evaluate incidence, risk factors, and prophylaxis.
Type
article
Institution
UNIL/CHUV/Unisanté + institutions partenaires
Périodique
Auteur(s)
Theochari, N.A.
Auteure/Auteur
Theochari, C.A.
Auteure/Auteur
Kokkinidis, D.G.
Auteure/Auteur
Kechagias, A.
Auteure/Auteur
Lyros, O.
Auteure/Auteur
Giannopoulos, S.
Auteure/Auteur
Mantziari, S.
Auteure/Auteur
Schizas, D.
Auteure/Auteur
Liens vers les personnes
Liens vers les unités
ISSN
1436-2813
Statut éditorial
Publié
Date de publication
2022-02
Volume
52
Numéro
2
Première page
171
Dernière page/numéro d’article
181
Peer-reviewed
Oui
Langue
anglais
Notes
Publication types: Journal Article ; Systematic Review
Publication Status: ppublish
Publication Status: ppublish
Résumé
Although esophagectomy remains the preferred treatment for esophageal cancer, it is still associated with a number of complications, including post-operative venous thromboembolism (VTE). The aim of this study was to summarize the reported incidence of VTE after esophagectomy, its risk factors, and prevention strategies.
We conducted a systematic search of the literature in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines.
Fourteen studies met our inclusion criteria and were selected in the present review. Overall, we identified 9768 patients who underwent esophagectomy, with a post-operative VTE rate of 4% (440 patients). The reported risk factors for VTE included advanced age, American Society of Anesthesiologists (ASA) class III or IV, a history of cardiovascular or pulmonary disease, and the implementation of preoperative chemo-radiotherapy. Postoperative acute respiratory distress syndrome was also associated with VTE. No universally applied prevention strategies for VTE after esophagectomy were identified in the literature.
Despite advances in perioperative care, VTE after esophagectomy still represents a source of morbidity for about 4% of patients. Low molecular weight heparin is suggested as the routine standard prophylactic regimen after esophageal cancer surgery.
We conducted a systematic search of the literature in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines.
Fourteen studies met our inclusion criteria and were selected in the present review. Overall, we identified 9768 patients who underwent esophagectomy, with a post-operative VTE rate of 4% (440 patients). The reported risk factors for VTE included advanced age, American Society of Anesthesiologists (ASA) class III or IV, a history of cardiovascular or pulmonary disease, and the implementation of preoperative chemo-radiotherapy. Postoperative acute respiratory distress syndrome was also associated with VTE. No universally applied prevention strategies for VTE after esophagectomy were identified in the literature.
Despite advances in perioperative care, VTE after esophagectomy still represents a source of morbidity for about 4% of patients. Low molecular weight heparin is suggested as the routine standard prophylactic regimen after esophageal cancer surgery.
Sujets
PID Serval
serval:BIB_CBCDD574A18F
PMID
Date de création
2021-03-27T15:03:37.513Z
Date de création dans IRIS
2025-05-20T23:54:19Z
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Nom
s00595-021-02260-2.pdf
Version du manuscrit
published
Taille
1.11 MB
Format
Adobe PDF
PID Serval
serval:BIB_CBCDD574A18F.P001
URN
urn:nbn:ch:serval-BIB_CBCDD574A18F6
Somme de contrôle
(MD5):aafc7734d62271eb86459d1ebcf6c2a3