Titre
Mechanism of analgesia induced by hypnosis and acupuncture: is there a difference?
Type
article
Institution
UNIL/CHUV/Unisanté + institutions partenaires
Périodique
Auteur(s)
Moret, V.
Auteure/Auteur
Forster, A.
Auteure/Auteur
Laverriere, M. C.
Auteure/Auteur
Lambert, H.
Auteure/Auteur
Gaillard, R. C.
Auteure/Auteur
Bourgeois, P.
Auteure/Auteur
Haynal, A.
Auteure/Auteur
Gemperle, M.
Auteure/Auteur
Buchser, E.
Auteure/Auteur
Liens vers les personnes
rgaillar
Liens vers les unités
ISSN
0304-3959
Statut éditorial
Publié
Date de publication
1991-05
Volume
45
Numéro
2
Première page
135
Dernière page/numéro d’article
40
Notes
Clinical Trial
Controlled Clinical Trial
Journal Article --- Old month value: May
Controlled Clinical Trial
Journal Article --- Old month value: May
Résumé
Hypnosis and acupuncture can alleviate experimentally induced pain but the mechanism of analgesia remains unclear for both techniques. Experimental pain was induced by cold pressor test (CPT) in 8 male volunteers. Analgesic effect of hypnosis (HA) and acupuncture (AA) was assessed before and after double-blind administration of placebo or naloxone, in a prospective, cross-over study. We found that pain intensity was significantly lower with HA as compared with AA, both with naloxone (P less than 0.001) and placebo (P less than 0.001). Within HA or AA groups, pain scores did not differ significantly when naloxone or placebo was administered. During AA, however, pain scores were similar to control values when naloxone was given (P = 0.05) but decreased significantly with placebo (P less than 0.002). Analog scales for pain intensity and pain relief showed a good correlation (r = 0.94). Plasma levels of beta-endorphins did not change significantly in any combination. Heart rate, peripheral arterial blood pressure and skin conductance were very insensitive indices to assess pain intensity or relief, as well as intensity of acupuncture stimulation or depth of hypnotic trance. We conclude: (1) HA and AA can significantly reduce pain from CPT, and HA is more effective than AA: (2) HA and AA are not primarily mediated by the opiate endorphin system; and (3) plasmatic levels of beta-endorphins are not significantly affected by either HA or AA nor by naloxone or placebo administration.
Sujets
PID Serval
serval:BIB_15D089BEDBB3
PMID
Date de création
2008-02-15T15:57:50.326Z
Date de création dans IRIS
2025-05-20T19:36:47Z