Titre

Hospitalization and mortality following non-attendance for hemodialysis according to dialysis day of the week: a European cohort study.

Type
article
Institution
UNIL/CHUV/Unisanté + institutions partenaires
Périodique
Auteur(s)
Fotheringham, J.
Auteure/Auteur
Smith, M.T.
Auteure/Auteur
Froissart, M.
Auteure/Auteur
Kronenberg, F.
Auteure/Auteur
Stenvinkel, P.
Auteure/Auteur
Floege, J.
Auteure/Auteur
Eckardt, K.U.
Auteure/Auteur
Wheeler, D.C.
Auteure/Auteur
Liens vers les personnes
Liens vers les unités
ISSN
1471-2369
Statut éditorial
Publié
Date de publication
2020-06-09
Volume
21
Numéro
1
Première page
218
Peer-reviewed
Oui
Langue
anglais
Notes
Publication types: Journal Article
Publication Status: epublish
Résumé
The extension of the interdialytic interval due to due to dialysis session non-attendance varies according to which session of the week the patient misses. The impact of this on subsequent hospitalization and mortality is unknown.
The ARO cohort study prospectively collected data from hemodialysis patients across 15 European countries on demography, comorbidity, laboratory, hospitalisation, mortality and individual hemodialysis sessions from 2007 to 2014. Event rates for death and hospitalisation according to dialysis day of the week were calculated for patients who attended the three previous scheduled hemodialysis sessions, who then on the next scheduled dialysis day either attended or did not attend. The hazard ratio for these events following non-attendance for the first compared to the second dialysis session of the week was estimated using Cox proportional hazards model adjusted for patient demographics.
3.8 million hemodialysis sessions in 9397 patients were analysed. The non-attendance rates for Monday/Wednesday/Friday sessions were 0.8, 0.9% & 1.4% respectively, and for Tuesday/Thursday/Saturday sessions were 0.6, 1.0% & 1.2% respectively. Compared to those who attended, for the 48-72 h between non-attendance and the next scheduled haemodialysis session, mortality significantly increased from 4.86 to 51.9/100 pt-yrs and hospitalisation increased from 0.58 to 2.1/yr. As time from the two-day break increased, the risk associated with non-attendance lessened: compared to missing the second hemodialysis session, missing the first session had a hazard ratio for mortality of 2.04 (95% CI 1.27-3.29), and for hospitalisation 1.78 (95% CI 1.29-2.47). In patients who attended their scheduled dialysis session and the three preceding, after the two-day break there were absolute increases in mortality (8.3 vs. 4.9/100 pt-yrs) and hospitalisation (1.0 vs. 0.6/yr for the rest of the week) comparable to previous studies.
In addition to hospitalisation and mortality increases seen after the two-day break, additional harm may be manifested in the greater increases in mortality and hospitalisation observed after non-attendance for the first hemodialysis session after the two-day break compared to missing other sessions.
Sujets

Adherence

Compliance

Hemodialysis

Hospitalisation

Interdialytic interva...

Mortality

PID Serval
serval:BIB_B236B317CE12
DOI
PMID
WOS
Permalien
Open Access
Oui
Date de création
2020-06-25T15:40:10.694Z
Date de création dans IRIS
2025-05-20T21:11:00Z
Fichier(s)
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Fotheringham non-attendance dialysis day of the week BMC Nephrol 2020.pdf

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published

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https://creativecommons.org/licenses/by/4.0

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1.35 MB

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PID Serval

serval:BIB_B236B317CE12.P001

URN

urn:nbn:ch:serval-BIB_B236B317CE121

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(MD5):5e742c8a215da12cc0483855306461ff

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12882_2020_1874_MOESM1_ESM.pdf

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supplementary

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341 KB

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Adobe PDF

PID Serval

serval:BIB_B236B317CE12.S001

Somme de contrôle

(MD5):d15fdff664b9dd4038676a9dba37f757