Titre
Diet Hypotheses in Light of the Microbiota Revolution: New Perspectives.
Type
synthèse (review)
Institution
UNIL/CHUV/Unisanté + institutions partenaires
Périodique
Auteur(s)
Wypych, T.P.
Auteure/Auteur
Marsland, B.J.
Auteure/Auteur
Liens vers les personnes
Liens vers les unités
ISSN
2072-6643
Statut éditorial
Publié
Date de publication
2017-05-24
Volume
9
Numéro
6
Première page
E537
Peer-reviewed
Oui
Langue
Notes
Publication types: Journal Article ; Review
Publication Status: epublish
Publication Status: epublish
Résumé
From an evolutionary standpoint, allergy has only recently emerged as a significant health problem. Various hypotheses were proposed to explain this, but they all indicated the importance of rapid lifestyle changes, which occurred in industrialized countries in the last few decades. In this review, we discuss evidence from epidemiological and experimental studies that indicate changes in dietary habits may have played an important role in this phenomenon. Based on the example of dietary fiber, we discuss molecular mechanisms behind this and point towards the importance of diet-induced changes in the microbiota. Finally, we reason that future studies unraveling mechanisms governing these changes, along with the development of better tools to manipulate microbiota composition in individuals will be crucial for the design of novel strategies to combat numerous inflammatory disorders, including atopic diseases.
Sujets
PID Serval
serval:BIB_C5B9F270BCCC
PMID
Open Access
Oui
Date de création
2017-06-13T15:36:24.162Z
Date de création dans IRIS
2025-05-21T01:55:17Z