Titre
CT imaging findings of invasive pulmonary fungal infections in hemato-oncologic children.
Type
article
Institution
UNIL/CHUV/Unisanté + institutions partenaires
Périodique
Auteur(s)
Alamo, L.
Auteure/Auteur
Ceppi, F.
Auteure/Auteur
Tenisch, E.
Auteure/Auteur
Beigelman-Aubry, C.
Auteure/Auteur
Liens vers les personnes
Liens vers les unités
ISSN
1869-4101
Statut éditorial
Publié
Date de publication
2024-12-12
Volume
15
Numéro
1
Première page
296
Peer-reviewed
Oui
Langue
anglais
Notes
Publication types: Journal Article
Publication Status: epublish
Publication Status: epublish
Résumé
Hemato-oncologic children form a heterogeneous group with a wide spectrum of ages, malignancy types, and immunosuppression grades during the different phases of their treatment. Immunosuppression is caused by multiple factors, including the malignancy itself, bone marrow suppression secondary to therapy, and wide use of steroids and antibiotics, among others. At the same time, the risk of infections in these patients remains high because of prolonged hospitalizations or the need for long-timing implanted devices between other features. In this context, a pulmonary fungal infection can rapidly turn into a life-threatening condition that requires early diagnosis and appropriate management. This pictorial essay illustrates the main imaging findings detected in chest computed tomography examinations performed in pediatric hemato-oncologic patients with proven pulmonary invasive fungal infections caused by Candida, Aspergillus, or Mucor. In addition, it describes useful clues for limiting differential diagnoses, reviews the literature on pediatric patients, and compares imaging findings in adults and children. CRITICAL RELEVANCE STATEMENT: The main fungal pathogens causing invasive fungal infections (IFI) in hemato-oncologic children are Candida, Aspergillus, and Mucor. This review describes the most frequently affected organs and the most common imaging findings detected in chest CT exams in children with pulmonary IFI. KEY POINTS: To review the main computed tomography imaging findings suggesting pulmonary invasive fungal infection (IFI) in hemato-oncologic children. To describe differences between pediatric and adult patients with proven pulmonary IFI. To provide useful clues for limiting the differential diagnosis of pulmonary IFI in pediatric patients.
PID Serval
serval:BIB_666040BE88C6
PMID
Open Access
Oui
Date de création
2024-12-16T15:25:26.592Z
Date de création dans IRIS
2025-05-20T23:58:00Z
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Nom
39666210_BIB_666040BE88C6.pdf
Version du manuscrit
published
Licence
https://creativecommons.org/licenses/by/4.0
Taille
2.18 MB
Format
Adobe PDF
PID Serval
serval:BIB_666040BE88C6.P001
URN
urn:nbn:ch:serval-BIB_666040BE88C60
Somme de contrôle
(MD5):bb69895f2335b6ac5d5673d35825140e