Titre
Expression pattern of aspartic proteinase antigens in aspergilli
Type
article
Institution
UNIL/CHUV/Unisanté + institutions partenaires
Auteur(s)
Reichard, U.
Auteure/Auteur
Monod, M.
Auteure/Auteur
Ruchel, R.
Auteure/Auteur
Liens vers les personnes
Liens vers les unités
ISSN
0933-7407
Statut éditorial
Publié
Date de publication
1996-04
Volume
39
Numéro
3-4
Première page
99
Dernière page/numéro d’article
101
Notes
Comparative Study
Journal Article --- Old month value: Mar-Apr
Journal Article --- Old month value: Mar-Apr
Résumé
Sporulating colonies of Aspergillus fumigatus, A. flavus, and A. niger were subjected to immunofluorescence using specific polyclonal antibodies against the aspergillopepsin PEP (EC 3.4.23.18), a secretory aspartic proteinase produced by A. fumigatus. The proteinase antigen was found mainly in developing conidiophores of aspergilli, in submerged mycelia and on the tips of growing aerial mycelia. Mature aerial hyphae and spores showed no immunofluorescence at all. Sporulating conidiophores revealed only weak activity in A. fumigatus and A. flavus. The distinct pattern of expression of the aspartic proteinase antigens suggests a role for such enzymes in the growth of hyphae and the development of conidiophores and thus for the sporulation process in aspergilli.
Sujets
PID Serval
serval:BIB_9CCBD3A51A93
PMID
Date de création
2008-01-25T15:46:49.729Z
Date de création dans IRIS
2025-05-21T00:39:47Z