Titre
Yersinia pseudotuberculosis serotype O:1 infection in a captive Seba's short tailed-fruit bat (Carollia perspicillata) colony in Switzerland.
Type
article
Institution
UNIL/CHUV/Unisanté + institutions partenaires
Périodique
Auteur(s)
Hahn, K.
Auteure/Auteur
Veiga, I.B.
Auteure/Auteur
Schediwy, M.
Auteure/Auteur
Wiederkehr, D.
Auteure/Auteur
Meniri, M.
Auteure/Auteur
Schneeberger, M.
Auteure/Auteur
den Broek, P.R.
Auteure/Auteur
Gurtner, C.
Auteure/Auteur
Fasel, N.J.
Auteure/Auteur
Kittl, S.
Auteure/Auteur
Fredriksson-Ahomaa, M.
Auteure/Auteur
Schmitt, S.
Auteure/Auteur
Stokar-Regenscheit, N.
Auteure/Auteur
Liens vers les personnes
Liens vers les unités
ISSN
1746-6148
Statut éditorial
Publié
Date de publication
2021-02-27
Volume
17
Numéro
1
Première page
92
Peer-reviewed
Oui
Langue
anglais
Notes
Publication types: Journal Article
Publication Status: epublish
Publication Status: epublish
Résumé
Between February and April 2016, a slight increase in mortality was observed in a colony consisting of 400 captive Seba's short-tailed bats (Carollia perspicillata). These animals cohabited with other nocturnal animal species in a dome of a private zoo in Switzerland.
Gross and histological analysis of two (14.3%) out of the 13 animals submitted for necropsy within this period revealed a necrosuppurative pneumonia, hepatitis, splenitis, enterocolitis, and endometritis, with abundant intralesional colonies of Gram-negative rods. Yersinia (Y.) pseudotuberculosis serotype O:1 and biotype 1 belonging to the sequence type ST90 was isolated from the affected organs in both animals. Following this diagnosis, ¼ of the colony (99 animals) was culled and submitted for gross and histopathological analysis, and a bacterial culture selective for Yersinia spp. of lung, liver, and spleen was performed. From these 99 animals, one gravid female was tested and found to be positive for Y. pseudotuberculosis in the absence of clinical symptoms and histopathological lesions. PCR analysis of altogether three bacterial isolates for virulence factors revealed the presence of the ail gene, and one isolate was also positive for the virF and yadA plasmid genes.
These findings suggest that Carollia perspicillata are susceptible to lethal yersiniosis but do not represent a regular reservoir for Y. pseudotuberculosis. Culling of ¼ of the population was sufficient to limit the spread of this infection among the colony. Moreover, no infections were detected in cohabitant nocturnal animals and caretakers, indicating that the zoonotic risk in this case was low.
Gross and histological analysis of two (14.3%) out of the 13 animals submitted for necropsy within this period revealed a necrosuppurative pneumonia, hepatitis, splenitis, enterocolitis, and endometritis, with abundant intralesional colonies of Gram-negative rods. Yersinia (Y.) pseudotuberculosis serotype O:1 and biotype 1 belonging to the sequence type ST90 was isolated from the affected organs in both animals. Following this diagnosis, ¼ of the colony (99 animals) was culled and submitted for gross and histopathological analysis, and a bacterial culture selective for Yersinia spp. of lung, liver, and spleen was performed. From these 99 animals, one gravid female was tested and found to be positive for Y. pseudotuberculosis in the absence of clinical symptoms and histopathological lesions. PCR analysis of altogether three bacterial isolates for virulence factors revealed the presence of the ail gene, and one isolate was also positive for the virF and yadA plasmid genes.
These findings suggest that Carollia perspicillata are susceptible to lethal yersiniosis but do not represent a regular reservoir for Y. pseudotuberculosis. Culling of ¼ of the population was sufficient to limit the spread of this infection among the colony. Moreover, no infections were detected in cohabitant nocturnal animals and caretakers, indicating that the zoonotic risk in this case was low.
PID Serval
serval:BIB_B436707F0602
PMID
Open Access
Oui
Date de création
2021-03-08T13:59:43.785Z
Date de création dans IRIS
2025-05-21T00:47:18Z
Fichier(s)![Vignette d'image]()
En cours de chargement...
Nom
33639950_BIB_B436707F0602.pdf
Version du manuscrit
published
Licence
https://creativecommons.org/licenses/by/4.0
Taille
1.39 MB
Format
Adobe PDF
PID Serval
serval:BIB_B436707F0602.P001
URN
urn:nbn:ch:serval-BIB_B436707F06026
Somme de contrôle
(MD5):56f74abeb36e9524b947d238d8082735