Titre
The weaker points of fish acute toxicity tests and how tests on embryos can solve some issues.
Type
synthèse (review)
Institution
UNIL/CHUV/Unisanté + institutions partenaires
Périodique
Auteur(s)
Wedekind, C.
Auteure/Auteur
von Siebenthal, B.
Auteure/Auteur
Gingold, R.
Auteure/Auteur
Liens vers les personnes
Liens vers les unités
ISSN
0269-7491
Statut éditorial
Publié
Date de publication
2007
Volume
148
Numéro
2
Première page
385
Dernière page/numéro d’article
389
Peer-reviewed
Oui
Langue
anglais
Résumé
Fish acute toxicity tests play an important role in environmental risk assessment and hazard classification because they allow for first estimates of the relative toxicity of various chemicals in various species. However, such tests need to be carefully interpreted. Here we shortly summarize the main issues which are linked to the genetics and the condition of the test animals, the standardized test situations, the uncertainty about whether a given test species can be seen as representative to a given fish fauna, the often missing knowledge about possible interaction effects, especially with micropathogens, and statistical problems like small sample sizes and, in some cases, pseudoreplication. We suggest that multi-factorial embryo tests on ecologically relevant species solve many of these issues, and we shortly explain how such tests could be done to avoid the weaker points of fish acute toxicity tests.
PID Serval
serval:BIB_8E675341770C
PMID
Date de création
2008-01-25T09:43:11.534Z
Date de création dans IRIS
2025-05-21T03:16:33Z