Titre
Physico-chemical characterization and oxidative reactivity evaluation of aged brake wear particles
Type
article
Institution
UNIL/CHUV/Unisanté + institutions partenaires
Périodique
Auteur(s)
Zhao, Jiayuan
Auteure/Auteur
Lewinski, Nastassja
Auteure/Auteur
Riediker, Michael
Auteure/Auteur
Liens vers les personnes
Liens vers les unités
ISSN
0278-6826
Statut éditorial
Publié
Date de publication
2015
Volume
49
Numéro
2
Première page
65
Dernière page/numéro d’article
74
Peer-reviewed
Oui
Langue
anglais
Résumé
Brake wear dust is a significant component of traffic emissions and has been linked to adverse health effects. Previous research found a strong oxidative stress response in cells exposed to freshly generated brake wear dust. We characterized aged dust collected from passenger vehicles, using microscopy and elemental analyses. Reactive oxygen species (ROS) generation was measured with acellular and cellular assays using 2′7-dichlorodihydrofluorescein dye. Microscopy analyses revealed samples to be heterogeneous particle mixtures with few nanoparticles detected. Several metals, primarily iron and copper, were identified. High oxygen concentrations suggested that the elements were oxidized. ROS were detected in the cell-free fluorescent test, while exposed cells were not dramatically activated by the concentrations used. The fact that aged brake wear samples have lower oxidative stress potential than fresh ones may relate to the highly oxidized or aged state of these particles, as well as their larger size and smaller reactive surface area.
PID Serval
serval:BIB_00285E7097E9
Open Access
Oui
Date de création
2015-02-13T10:26:56.307Z
Date de création dans IRIS
2025-05-20T17:04:32Z
Fichier(s)![Vignette d'image]()
En cours de chargement...
Nom
BIB_00285E7097E9.P001.pdf
Version du manuscrit
published
Taille
539.73 KB
Format
Adobe PDF
PID Serval
serval:BIB_00285E7097E9.P001
URN
urn:nbn:ch:serval-BIB_00285E7097E99
Somme de contrôle
(MD5):f48cdca449b8fdae3eee68401166f368