Titre
Recording of ventral posterior lateral thalamus neuron response to contact heat evoked potential in patient with neurogenic pain
Type
étude de cas
Institution
UNIL/CHUV/Unisanté + institutions partenaires
Périodique
Auteur(s)
Pralong, E.
Auteure/Auteur
Pollo, C.
Auteure/Auteur
Bloch, J.
Auteure/Auteur
Villemure, J. G.
Auteure/Auteur
Daniel, R. T.
Auteure/Auteur
Tetreault, M. H.
Auteure/Auteur
Debatisse, D.
Auteure/Auteur
Liens vers les personnes
Liens vers les unités
ISSN
0304-3940
Statut éditorial
Publié
Date de publication
2004-09
Volume
367
Numéro
3
Première page
332
Dernière page/numéro d’article
5
Peer-reviewed
Oui
Notes
Case Reports
Comparative Study
Journal Article --- Old month value: Sep 9
Comparative Study
Journal Article --- Old month value: Sep 9
Résumé
Microrecording of single unit response to contact heat-evoked potential (CHEP) were performed in right ventral posterior lateral (VPL) thalamus during deep brain stimulation (DBS) surgery in a patient with chronic neurogenic pain. In our patient, neurons (n = 10) recorded in the ventral thalamus fired at a higher rate of 40 Hz compared to neurons recorded in Parkinsonian patients (24 Hz). Contact heat was applied by a fast heating and cooling probe of 5 cm2 area on the dermatome C6 territory of the left hand. One out of four thalamic cells located in the VPL responded repetitively 325 ms after the peak temperature was reached with a burst of action potential, suggesting A-delta fibre activation. This observation supports the use of CHEP for mapping nociceptive neurons location during DBS surgery for intractable pain.
Sujets
PID Serval
serval:BIB_0714871C8D55
PMID
Date de création
2008-02-06T09:03:04.884Z
Date de création dans IRIS
2025-05-20T19:08:33Z