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  4. Assessing the applicability and appropriateness of ChatGPT in answering clinical pharmacy questions.
 
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Titre

Assessing the applicability and appropriateness of ChatGPT in answering clinical pharmacy questions.

Type
article
Institution
UNIL/CHUV/Unisanté + institutions partenaires
Périodique
Annales Pharmaceutiques Françaises  
Auteur(s)
Fournier, A.
Auteure/Auteur
Fallet, C.
Auteure/Auteur
Sadeghipour, F.
Auteure/Auteur
Perrottet, N.
Auteure/Auteur
Liens vers les personnes
Sadeghipour, Farshid  
Liens vers les unités
Pharmacie  
Sciences pharmaceutiques cliniques  
ISSN
0003-4509
Statut éditorial
Publié
Date de publication
2024-05
Volume
82
Numéro
3
Première page
507
Dernière page/numéro d’article
513
Peer-reviewed
Oui
Langue
anglais
Notes
Publication types: Journal Article
Publication Status: ppublish
Résumé
Clinical pharmacists rely on different scientific references to ensure appropriate, safe, and cost-effective drug use. Tools based on artificial intelligence (AI) such as ChatGPT (Generative Pre-trained Transformer) could offer valuable support. The objective of this study was to assess ChatGPT's capacity to correctly respond to clinical pharmacy questions asked by healthcare professionals in our university hospital.
ChatGPT's capacity to respond correctly to the last 100 consecutive questions recorded in our clinical pharmacy database was assessed. Questions were copied from our FileMaker Pro database and pasted into ChatGPT March 14 version online platform. The generated answers were then copied verbatim into an Excel file. Two blinded clinical pharmacists reviewed all the questions and the answers given by the software. In case of disagreements, a third blinded pharmacist intervened to decide.
Documentation-related issues (n=36) and drug administration mode (n=30) were preponderantly recorded. Among 69 applicable questions, the rate of correct answers varied from 30 to 57.1% depending on questions type with a global rate of 44.9%. Regarding inappropriate answers (n=38), 20 were incorrect, 18 gave no answers and 8 were incomplete with 8 answers belonging to 2 different categories. No better answers than the pharmacists were observed.
ChatGPT demonstrated a mitigated performance in answering clinical pharmacy questions. It should not replace human expertise as a high rate of inappropriate answers was highlighted. Future studies should focus on the optimization of ChatGPT for specific clinical pharmacy questions and explore the potential benefits and limitations of integrating this technology into clinical practice.
Sujets

Humans

Artificial Intelligen...

Pharmacists

Databases, Factual

Health Personnel

Pharmacy

Artificial intelligen...

ChatGPT

Clinical pharmacy

Grands modèles de lan...

Healthcare profession...

Intelligence artifici...

Large language models...

Pharmacie clinique

Questions fréquentes ...

PID Serval
serval:BIB_F6682B442781
DOI
10.1016/j.pharma.2023.11.001
PMID
37992892
WOS
001288575800001
Permalien
https://iris.unil.ch/handle/iris/255581
Date de création
2023-11-23T13:14:44.724Z
Date de création dans IRIS
2025-05-21T07:01:25Z
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