Titre
Three-dimensional echo planar imaging with controlled aliasing: A sequence for high temporal resolution functional MRI.
Type
article
Institution
UNIL/CHUV/Unisanté + institutions partenaires
Périodique
Auteur(s)
Narsude, M.
Auteure/Auteur
Gallichan, D.
Auteure/Auteur
van der Zwaag, W.
Auteure/Auteur
Gruetter, R.
Auteure/Auteur
Marques, J.P.
Auteure/Auteur
Liens vers les personnes
Liens vers les unités
ISSN
1522-2594
Statut éditorial
Publié
Date de publication
2016-06
Volume
75
Numéro
6
Première page
2350
Dernière page/numéro d’article
2361
Peer-reviewed
Oui
Langue
anglais
Notes
Publication types: Journal Article
Publication Status: ppublish
Publication Status: ppublish
Résumé
In this work, we combine three-dimensional echo planar imaging (3D-EPI) with controlled aliasing to substantially increase temporal resolution in whole-brain functional MRI (fMRI) while minimizing geometry-factor (g-factor) losses.
The study was performed on a 7 Tesla scanner equipped with a 32-channel receive coil. The proposed 3D-EPI-CAIPI sequence was evaluated for: (i) image quality, compared with a conventionally undersampled parallel imaging acquisition; (ii) temporal resolution, the ability to sample and remove physiological signal fluctuations from the fMRI signal of interest and (iii) the ability to distinguish small changes in hemodynamic responses in an event-related fMRI experiment.
Whole-brain fMRI data with a voxel size of 2 × 2 × 2 mm(3) and temporal resolution of 371 ms could be acquired with acceptable image quality. Ten-fold parallel imaging accelerated 3D-EPI-CAIPI data were shown to lower the maximum g-factor losses up to 62% with respect to a 10-fold accelerated 3D-EPI dataset. FMRI with 400 ms temporal resolution allowed the detection of time-to-peak variations in functional responses due to multisensory facilitation in temporal, occipital and frontal cortices.
3D-EPI-CAIPI allows increased temporal resolution that enables better characterization of physiological noise, thus improving sensitivity to signal changes of interest. Furthermore, subtle changes in hemodynamic response dynamics can be studied in shorter scan times by avoiding the need for jittering. Magn Reson Med 75:2350-2361, 2016. © 2015 Wiley Periodicals, Inc.
The study was performed on a 7 Tesla scanner equipped with a 32-channel receive coil. The proposed 3D-EPI-CAIPI sequence was evaluated for: (i) image quality, compared with a conventionally undersampled parallel imaging acquisition; (ii) temporal resolution, the ability to sample and remove physiological signal fluctuations from the fMRI signal of interest and (iii) the ability to distinguish small changes in hemodynamic responses in an event-related fMRI experiment.
Whole-brain fMRI data with a voxel size of 2 × 2 × 2 mm(3) and temporal resolution of 371 ms could be acquired with acceptable image quality. Ten-fold parallel imaging accelerated 3D-EPI-CAIPI data were shown to lower the maximum g-factor losses up to 62% with respect to a 10-fold accelerated 3D-EPI dataset. FMRI with 400 ms temporal resolution allowed the detection of time-to-peak variations in functional responses due to multisensory facilitation in temporal, occipital and frontal cortices.
3D-EPI-CAIPI allows increased temporal resolution that enables better characterization of physiological noise, thus improving sensitivity to signal changes of interest. Furthermore, subtle changes in hemodynamic response dynamics can be studied in shorter scan times by avoiding the need for jittering. Magn Reson Med 75:2350-2361, 2016. © 2015 Wiley Periodicals, Inc.
PID Serval
serval:BIB_460122B422BF
PMID
Date de création
2015-07-30T14:56:54.232Z
Date de création dans IRIS
2025-05-20T20:45:45Z