Titre
Process variations between Swiss units treating neonates with hypoxic-ischemic encephalopathy and their effect on short-term outcome.
Type
article
Institution
UNIL/CHUV/Unisanté + institutions partenaires
Périodique
Auteur(s)
Adams, M.
Auteure/Auteur
Brotschi, B.
Auteure/Auteur
Birkenmaier, A.
Auteure/Auteur
Schwendener, K.
Auteure/Auteur
Rathke, V.
Auteure/Auteur
Kleber, M.
Auteure/Auteur
Hagmann, C.
Auteure/Auteur
Contributrices/contributeurs
Bassler, D.
Natalucci, G.
Böttger, S.
Frey, B.
Bernet, V.
Grass, B.
Rogdo, B.
Hoigné, I.
Stocker, M.
Berger, T.M.
Fontana, M.
Hegi, L.
Meyer, P.
Konetzny, G.
Schulzke, S.M.
Wellmann, S.
Hug, M.
Humpl, T.
Wagner, B.
Daetwyler, K.
Riedel, T.
Scharrer, B.
Binz, N.
Truttmann, A.
Schneider, J.
Groupes de travail
Swiss National Asphyxia and Cooling Register Group
Liens vers les personnes
Liens vers les unités
ISSN
1476-5543
Statut éditorial
Publié
Date de publication
2021-12
Volume
41
Numéro
12
Première page
2804
Dernière page/numéro d’article
2812
Peer-reviewed
Oui
Langue
anglais
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't
Publication Status: ppublish
Publication Status: ppublish
Résumé
To compare therapeutic hypothermia (TH) treatment of term and near-term neonates with hypoxic-ischemic encephalopathy (HIE) between neonatal units.
Population-based, retrospective analysis of TH initiation and maintenance, and of diagnostic imaging. The comparison between units was based on crude data analysis, indirect standardization, and adjusted logistic regression.
TH was provided to 570 neonates with HIE between 2011 and 2018 in 10 Swiss units. We excluded 121 off-protocol cooled neonates to avoid selection bias. Of the remaining 449 neonates, the outcome was favorable to international benchmarks, but there were large unit-to-unit variations in baseline perinatal data and TH management. A total of 5% neonates did not reach target temperature within 7 h (3-10% between units), and 29% experienced over- or undercooling (0-38%).
Although the neonates had favorable short-term outcomes, areas for improvement remain for Swiss units in both process and outcome measures.
Population-based, retrospective analysis of TH initiation and maintenance, and of diagnostic imaging. The comparison between units was based on crude data analysis, indirect standardization, and adjusted logistic regression.
TH was provided to 570 neonates with HIE between 2011 and 2018 in 10 Swiss units. We excluded 121 off-protocol cooled neonates to avoid selection bias. Of the remaining 449 neonates, the outcome was favorable to international benchmarks, but there were large unit-to-unit variations in baseline perinatal data and TH management. A total of 5% neonates did not reach target temperature within 7 h (3-10% between units), and 29% experienced over- or undercooling (0-38%).
Although the neonates had favorable short-term outcomes, areas for improvement remain for Swiss units in both process and outcome measures.
PID Serval
serval:BIB_EC7D73520751
PMID
Open Access
Oui
Date de création
2024-02-27T10:07:03.084Z
Date de création dans IRIS
2025-05-21T06:49:29Z
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34290374_BIB_EC7D73520751.pdf
Version du manuscrit
published
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694.59 KB
Format
Adobe PDF
PID Serval
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