Titre
Psychotropic medication use in the child and adolescent psychiatry wards of a French hospital.
Type
article
Institution
Externe
Périodique
Pharmacy world & science
Auteur(s)
Winterfeld, U.
Auteure/Auteur
Le Heuzey, M.F.
Auteure/Auteur
Acquaviva, E.
Auteure/Auteur
Mouren, M.C.
Auteure/Auteur
Brion, F.
Auteure/Auteur
Bourdon, O.
Auteure/Auteur
Liens vers les personnes
ISSN
0928-1231
Statut éditorial
Publié
Date de publication
2008-10
Volume
30
Numéro
5
Première page
600
Dernière page/numéro d’article
604
Peer-reviewed
Oui
Langue
anglais
Notes
Publication types: Journal Article
Publication Status: ppublish
Publication Status: ppublish
Résumé
The aim of this study was to investigate the use of psychotropic medication in children and adolescents hospitalised in a psychiatric ward.
A prospective analysis of psychotropic drug prescriptions was conducted for all patients hospitalised in two acute psychiatric hospitalisation units of a paediatric teaching hospital in Paris, France. The study group consisted of 187 patients and was characterised in terms of age, sex, prior psychiatric hospitalisation and DSM-IV-Tr diagnosis. All prescriptions were assessed for off-label use.
Overall, 46% of patients received at least one dose of psychotropic medication. Antipsychotic drugs were the most frequently prescribed drugs (44%), regardless of diagnosis. Ninety percent of patients who received antipsychotic drugs did not have psychosis. We found that 69% of the 421 prescriptions written were for off-label uses. The percentage distribution of off-label prescriptions by medication class was as follows: antipsychotic drugs, 90%; anxiolytics, 28%; stimulants, 26%; antidepressants, 89%; antiepileptic drugs, 89% and antiparkinsonian drugs, 91%.
The extensive use of drugs for off-label indications in children and adolescents suggests that prospective post-marketing studies should be carried out to evaluate efficacy and safety.
A prospective analysis of psychotropic drug prescriptions was conducted for all patients hospitalised in two acute psychiatric hospitalisation units of a paediatric teaching hospital in Paris, France. The study group consisted of 187 patients and was characterised in terms of age, sex, prior psychiatric hospitalisation and DSM-IV-Tr diagnosis. All prescriptions were assessed for off-label use.
Overall, 46% of patients received at least one dose of psychotropic medication. Antipsychotic drugs were the most frequently prescribed drugs (44%), regardless of diagnosis. Ninety percent of patients who received antipsychotic drugs did not have psychosis. We found that 69% of the 421 prescriptions written were for off-label uses. The percentage distribution of off-label prescriptions by medication class was as follows: antipsychotic drugs, 90%; anxiolytics, 28%; stimulants, 26%; antidepressants, 89%; antiepileptic drugs, 89% and antiparkinsonian drugs, 91%.
The extensive use of drugs for off-label indications in children and adolescents suggests that prospective post-marketing studies should be carried out to evaluate efficacy and safety.
PID Serval
serval:BIB_5587B4B63FF5
PMID
URL éditeur
Date de création
2021-06-09T07:32:04.679Z
Date de création dans IRIS
2025-05-20T14:39:24Z