Titre

Impairment and disability in 20 CIDP patients according to disease activity status.

Type
article
Institution
UNIL/CHUV/Unisanté + institutions partenaires
Périodique
Auteur(s)
Panaite, P.A.
Auteure/Auteur
Renaud, S.
Auteure/Auteur
Kraftsik, R.
Auteure/Auteur
Steck, A.J.
Auteure/Auteur
Kuntzer, T.
Auteure/Auteur
Liens vers les personnes
Liens vers les unités
ISSN
1529-8027
Statut éditorial
Publié
Date de publication
2013
Volume
18
Numéro
3
Première page
241
Dernière page/numéro d’article
246
Peer-reviewed
Oui
Langue
anglais
Résumé
Twenty patients with chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) meeting the EFNS/PNS criteria were examined in order to assess differences/similarities between the various grading systems according to CIDP disease activity status (CDAS). A principal component (PC) analysis and the correlations between the following scores were performed: Neurological Symptom Score; MRC sum score; Neurological Impairment Score; Hammersmith Functional Motor Scale; Inflammatory Neuropathy Cause and Treatment (INCAT) Sensory Sum Score; Overall Disability Sum Score; INCAT Disability Score; Rasch-built Overall Disability Scale. Our analysis outlined two main sets of scales, with high influence in the top two PCs. The first PC that best explained the variability within the cohort consisted of CDAS, general disability scores and motor scores; these parameters were also strongly correlated amongst each other. The second PC explained less the variability and consisted mainly of sensory scores and disease duration; these parameters did not correlate with the scores of the first PC or with the CDAS. Our findings suggest separating screening for motor and sensory deficits when evaluating CIDP patients, as only the motor scores correlate with CDAS.
PID Serval
serval:BIB_1592DBD6FF5B
DOI
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Date de création
2014-02-07T17:58:09.364Z
Date de création dans IRIS
2025-05-20T19:08:02Z
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BIB_1592DBD6FF5B.P001.pdf

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published

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447.66 KB

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Adobe PDF

PID Serval

serval:BIB_1592DBD6FF5B.P001

URN

urn:nbn:ch:serval-BIB_1592DBD6FF5B3

Somme de contrôle

(MD5):e8079248cf080629903e7d7c3aec09cd