Titre
Physiological profile during venovenous perfusion in dogs using a polypropylene membrane lung with secondary flows
Type
article
Institution
UNIL/CHUV/Unisanté + institutions partenaires
Périodique
Auteur(s)
Gardaz, J. P.
Auteure/Auteur
Dorrington, K. L.
Auteure/Auteur
Py, P.
Auteure/Auteur
Schweizer, A.
Auteure/Auteur
Liens vers les personnes
Liens vers les unités
ISSN
0141-5425
Statut éditorial
Publié
Date de publication
1988-01
Volume
10
Numéro
1
Première page
74
Dernière page/numéro d’article
81
Notes
Comparative Study
Journal Article
Research Support, Non-U.S. Gov't --- Old month value: Jan
Journal Article
Research Support, Non-U.S. Gov't --- Old month value: Jan
Résumé
Venovenous perfusion has been conducted in 12 healthy dogs to examine carbon dioxide (CO2) transfer and haemocompatibility over 9 h during total extracorporeal CO2 removal using a microporous polypropylene membrane lung with secondary flows in the blood channel. The anaesthetized animals were maintained normocapnic by including CO2 in the inspired gases. The CO2 removal was achieved using 0.631 m2 of active membrane, at a pulsatile Reynolds number of 50, and a CO2 extraction from blood of 17.8 ml (STP) dl-1. Gas exchange remained constant during the perfusions. Several aspects of our results suggest that the haemocompatibility of a system of the kind used here is at least as favourable as that of a steady flow device using a continuous silicone rubber membrane of equivalent gas transfer capability.
Sujets
PID Serval
serval:BIB_7A2EA78A4256
PMID
Date de création
2008-01-28T09:48:15.399Z
Date de création dans IRIS
2025-05-21T01:37:07Z