Titre
Better Pandemic Influenza Preparedness through Adjuvant Technology Transfer: Challenges and Lessons Learned.
Type
synthèse (review)
Institution
Externe
Périodique
Auteur(s)
Lemoine, C.H.
Auteure/Auteur
Nidom, R.V.
Auteure/Auteur
Ventura, R.
Auteure/Auteur
Indrasari, S.
Auteure/Auteur
Normalina, I.
Auteure/Auteur
Santoso, K.P.
Auteure/Auteur
Derouet, F.
Auteure/Auteur
Barnier-Quer, C.
Auteure/Auteur
Borchard, G.
Auteure/Auteur
Collin, N.
Auteure/Auteur
Nidom, C.A.
Auteure/Auteur
Liens vers les personnes
ISSN
2076-393X
Statut éditorial
Publié
Date de publication
2021-05-05
Volume
9
Numéro
5
Première page
461
Peer-reviewed
Oui
Langue
anglais
Notes
Publication types: Journal Article ; Review
Publication Status: epublish
Publication Status: epublish
Résumé
Adequate global vaccine coverage during an influenza pandemic is essential to mitigate morbidity, mortality, and economic impact. Vaccine development and production needs to be sufficient to meet a vast global demand, requiring international cooperation and local vaccine production capacity, especially in resource-constrained countries. The use of adjuvants is one approach to augment the number of available vaccine doses and to overcome potential vaccine shortages. Appropriately selected adjuvant technologies can decrease the amount of vaccine antigen required per dose, may broaden or lengthen the conferred protection against disease, and may even allow protective single-dose vaccination. Here we describe a technology transfer collaboration between Switzerland and Indonesia that led to the establishment of a vaccine formulation platform in Surabaya which involved the transfer of equipment and expertise to enable research and development of adjuvanted vaccine formulations and delivery systems. This new Indonesian capability aims to facilitate local and regional access to know-how relating to adjuvanted vaccine formulations, thus promoting their application to local vaccine developers. In this review, we aim to share the "lessons learned" from this project to both support and inspire future scientific collaborations of a similar nature.
PID Serval
serval:BIB_A932D62586EB
PMID
Open Access
Oui
Date de création
2021-06-14T12:13:48.574Z
Date de création dans IRIS
2025-05-21T00:18:06Z
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Nom
34063131_BIB_A932D62586EB.pdf
Version du manuscrit
published
Licence
https://creativecommons.org/licenses/by/4.0
Taille
1.77 MB
Format
Adobe PDF
PID Serval
serval:BIB_A932D62586EB.P001
Somme de contrôle
(MD5):193736a95e8f2ab84011c3e7c52c9cb5