Titre
Iterative Reconstructions in Reduced-Dose CT: Which Type Ensures Diagnostic Image Quality in Young Oncology Patients?
Type
article
Institution
UNIL/CHUV/Unisanté + institutions partenaires
Périodique
Auteur(s)
Pauchard, B.
Auteure/Auteur
Higashigaito, K.
Auteure/Auteur
Lamri-Senouci, A.
Auteure/Auteur
Knebel, J.F.
Auteure/Auteur
Berthold, D.
Auteure/Auteur
Verdun, F.R.
Auteure/Auteur
Alkadhi, H.
Auteure/Auteur
Schmidt, S.
Auteure/Auteur
Liens vers les personnes
Liens vers les unités
ISSN
1878-4046
Statut éditorial
Publié
Date de publication
2017-09
Volume
24
Numéro
9
Première page
1114
Dernière page/numéro d’article
1124
Peer-reviewed
Oui
Langue
anglais
Notes
Publication types: Comparative Study ; Journal Article
Publication Status: ppublish
Publication Status: ppublish
Résumé
To compare adaptive statistical iterative reconstruction (ASIR) and model-based iterative reconstruction (MBIR) algorithms for reduced-dose computed tomography (CT).
Forty-four young oncology patients (mean age 30 ± 9 years) were included. After routine thoraco-abdominal CT (dose 100%, average CTDI javax.xml.bind.JAXBElement@e7f585f 9.1 ± 2.4 mGy, range 4.4-16.9 mGy), follow-up CT was acquired at 50% (average CTDI javax.xml.bind.JAXBElement@2e35610f 4.5 ± 1.2 mGy, range 2.2-8.4 mGy) in 29 patients additionally at 20% dose (average CTDI javax.xml.bind.JAXBElement@37ad3473 1.9 ± 0.5 mGy, range 0.9-3.4 mGy). Each reduced-dose CT was reconstructed using both ASIR and MBIR. Four radiologists (two juniors and two seniors) blinded to dose and technique read each set of CT images regarding objective and subjective image qualities (high- or low-contrast structures), subjective noise or pixilated appearance, diagnostic confidence, and lesion detection.
At all dose levels, objective image noise was significantly lower with MBIR than with ASIR (P < 0.001). The subjective image quality for low-contrast structures was significantly higher with MBIR than with ASIR (P < 0.001). Reduced-dose abdominal CT images of patients with higher body mass index (BMI) were read with significantly higher diagnostic confidence than images of slimmer patients (P < 0.001) and had higher subjective image quality, regardless of technique. Although MBIR images appeared significantly more pixilated than ASIR images, they were read with higher diagnostic confidence, especially by juniors (P < 0.001).
Reduced-dose CT during the follow-up of young oncology patients should be reconstructed with MBIR to ensure diagnostic quality. Elevated body mass index does not hamper the quality of reduced-dose CT.
Forty-four young oncology patients (mean age 30 ± 9 years) were included. After routine thoraco-abdominal CT (dose 100%, average CTDI javax.xml.bind.JAXBElement@e7f585f 9.1 ± 2.4 mGy, range 4.4-16.9 mGy), follow-up CT was acquired at 50% (average CTDI javax.xml.bind.JAXBElement@2e35610f 4.5 ± 1.2 mGy, range 2.2-8.4 mGy) in 29 patients additionally at 20% dose (average CTDI javax.xml.bind.JAXBElement@37ad3473 1.9 ± 0.5 mGy, range 0.9-3.4 mGy). Each reduced-dose CT was reconstructed using both ASIR and MBIR. Four radiologists (two juniors and two seniors) blinded to dose and technique read each set of CT images regarding objective and subjective image qualities (high- or low-contrast structures), subjective noise or pixilated appearance, diagnostic confidence, and lesion detection.
At all dose levels, objective image noise was significantly lower with MBIR than with ASIR (P < 0.001). The subjective image quality for low-contrast structures was significantly higher with MBIR than with ASIR (P < 0.001). Reduced-dose abdominal CT images of patients with higher body mass index (BMI) were read with significantly higher diagnostic confidence than images of slimmer patients (P < 0.001) and had higher subjective image quality, regardless of technique. Although MBIR images appeared significantly more pixilated than ASIR images, they were read with higher diagnostic confidence, especially by juniors (P < 0.001).
Reduced-dose CT during the follow-up of young oncology patients should be reconstructed with MBIR to ensure diagnostic quality. Elevated body mass index does not hamper the quality of reduced-dose CT.
Sujets
PID Serval
serval:BIB_D9286BF48739
PMID
Open Access
Oui
Date de création
2017-04-11T16:52:59.658Z
Date de création dans IRIS
2025-05-21T00:57:06Z
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Nom
28365232.pdf
Version du manuscrit
published
Taille
1.41 MB
Format
Adobe PDF
PID Serval
serval:BIB_D9286BF48739.P001
URN
urn:nbn:ch:serval-BIB_D9286BF487392
Somme de contrôle
(MD5):a190a9d6251298b063a9c05705187edd