Titre
Obesity markers and estimated 10-year fatal cardiovascular risk in Switzerland.
Type
article
Institution
UNIL/CHUV/Unisanté + institutions partenaires
Auteur(s)
Marques-Vidal, P.
Auteure/Auteur
Bochud, M.
Auteure/Auteur
Mooser, V.
Auteure/Auteur
Paccaud, F.
Auteure/Auteur
Waeber, G.
Auteure/Auteur
Vollenweider, P.
Auteure/Auteur
Liens vers les personnes
Liens vers les unités
ISSN
1590-3729
Statut éditorial
Publié
Date de publication
2009
Volume
19
Numéro
7
Première page
462
Dernière page/numéro d’article
468
Peer-reviewed
Oui
Langue
anglais
Résumé
BACKGROUND AND AIM: There is an ongoing debate on which obesity marker better predicts cardiovascular disease (CVD). In this study, the relationships between obesity markers and high (>5%) 10-year risk of fatal CVD were assessed. METHODS AND RESULTS: A cross-sectional study was conducted including 3047 women and 2689 men aged 35-75years. Body fat percentage was assessed by tetrapolar bioimpedance. CVD risk was assessed using the SCORE risk function and gender- and age-specific cut points for body fat were derived. The diagnostic accuracy of each obesity marker was evaluated through receiver operating characteristics (ROC) analysis. In men, body fat presented a higher correlation (r=0.31) with 10-year CVD risk than waist/hip ratio (WHR, r=0.22), waist (r=0.22) or BMI (r=0.19); the corresponding values in women were 0.18, 0.15, 0.11 and 0.05, respectively (all p<0.05). In both genders, body fat showed the highest area under the ROC curve (AUC): in men, the AUC (95% confidence interval) were 76.0 (73.8-78.2), 67.3 (64.6-69.9), 65.8 (63.1-68.5) and 60.6 (57.9-63.5) for body fat, WHR, waist and BMI, respectively. In women, the corresponding values were 72.3 (69.2-75.3), 66.6 (63.1-70.2), 64.1 (60.6-67.6) and 58.8 (55.2-62.4). The use of the body fat percentage criterion enabled the capture of three times more subjects with high CVD risk than the BMI criterion, and almost twice as much as the WHR criterion. CONCLUSION: Obesity defined by body fat percentage is more related with 10-year risk of fatal CVD than obesity markers based on WHR, waist or BMI.
Sujets
PID Serval
serval:BIB_21B0DE7A8AE4
PMID
Date de création
2009-03-02T17:46:50.025Z
Date de création dans IRIS
2025-05-20T16:52:07Z
Fichier(s)![Vignette d'image]()
En cours de chargement...
Nom
BIB_21B0DE7A8AE4.P001.pdf
Version du manuscrit
preprint
Taille
220.48 KB
Format
Adobe PDF
PID Serval
serval:BIB_21B0DE7A8AE4.P001
URN
urn:nbn:ch:serval-BIB_21B0DE7A8AE40
Somme de contrôle
(MD5):3eaf72a2951c382b7621f20014e75bc6