Titre
Lung cancer screening: current situation and perspective.
Type
synthèse (review)
Institution
UNIL/CHUV/Unisanté + institutions partenaires
Périodique
Auteur(s)
Guessous, Idris
Auteure/Auteur
Cornuz, Jacques
Auteure/Auteur
Paccaud, Fred
Auteure/Auteur
Liens vers les personnes
Liens vers les unités
ISSN
1424-7860
Statut éditorial
Publié
Date de publication
2007
Volume
137
Numéro
21-22
Première page
304
Dernière page/numéro d’article
311
Peer-reviewed
Oui
Langue
anglais
Notes
http://www.smw.ch/docs/pdf200x/2007/21/smw-11582.PDF
Résumé
Worldwide, lung cancer is the most common cancer in terms of both incidence and mortality with 1,04 million new cases per year and 921000 deaths, with the highest rates currently observed in Europe and North America. Once diagnosed, the 5-year survival rate for lung cancer in Europe fluctuates between 8% and 12%. Smoking is found in 90% of lung cancer cases. A successful, straightforward preventive strategy to reduce the incidence of the disease is a sustained prevention of tobacco consumption. However, because of the persistent risk among former smokers, early treatment following early diagnosis is still considered as potential development. There is currently no recommended screening strategy for lung cancer, reflecting the negative results of trials showing no mortality reduction following screening programs using chest X-ray and sputum examination. Low dose computed tomography has been recently assessed as a screening tool in observational studies suggesting better impact than the one obtained with chest X-ray. Five RCTs are currently under way to evaluate low dose computed tomography as a screening tool for lung cancer, with a total of 133,000 subjects. First results are expected for2007. Until the completion of these studies, wild screening intervention should be avoided.
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PMID
Date de création
2008-01-29T13:57:19.495Z
Date de création dans IRIS
2025-05-20T22:10:31Z
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