Titre
Messages from the first International Conference on Clinical Metagenomics (ICCMg).
Type
recension de livre
Institution
UNIL/CHUV/Unisanté + institutions partenaires
Périodique
Auteur(s)
Ruppé, E.
Auteure/Auteur
Greub, G.
Auteure/Auteur
Schrenzel, J.
Auteure/Auteur
Liens vers les personnes
Liens vers les unités
ISSN
1769-714X
Statut éditorial
Publié
Date de publication
2017
Volume
19
Numéro
4-5
Première page
223
Dernière page/numéro d’article
228
Peer-reviewed
Oui
Langue
anglais
Notes
Publication types: Journal Article
Publication Status: ppublish
Publication Status: ppublish
Résumé
Metagenomics is recently entering in the clinical microbiology and an increasing number of diagnostic laboratories are now proposing the sequencing & annotation of bacterial genomes and/or the analysis of clinical samples by direct or PCR-based metagenomics with short time to results. In this context, the first International Conference on Clinical Metagenomics (ICCMg) was held in Geneva in October 2016 and several key aspects have been discussed including: i) the need for improved resolution, ii) the importance of interpretation given the common occurrence of sequence contaminants, iii) the need for improved bioinformatic pipelines, iv) the bottleneck of DNA extraction, v) the importance of gold standards, vi) the need to further reduce time to results, vii) how to improve data sharing, viii) the applications of bacterial genomics and clinical metagenomics in better adapting therapeutics and ix) the impact of metagenomics and new sequencing technologies in discovering new microbes. Further efforts in term of reduced turnaround time, improved quality and lower costs are however warranted to fully translate metagenomics in clinical applications.
PID Serval
serval:BIB_AAEF74ECE40E
PMID
Date de création
2017-02-14T10:06:01.640Z
Date de création dans IRIS
2025-05-21T00:20:55Z