Titre
Standardized EEG interpretation in patients after cardiac arrest: Correlation with other prognostic predictors.
Type
article
Institution
UNIL/CHUV/Unisanté + institutions partenaires
Périodique
Auteur(s)
Beuchat, I.
Auteure/Auteur
Solari, D.
Auteure/Auteur
Novy, J.
Auteure/Auteur
Oddo, M.
Auteure/Auteur
Rossetti, A.O.
Auteure/Auteur
Liens vers les personnes
Liens vers les unités
ISSN
1873-1570
Statut éditorial
Publié
Date de publication
2018-05
Volume
126
Première page
143
Dernière page/numéro d’article
146
Peer-reviewed
Oui
Langue
anglais
Notes
Publication types: Journal Article
Publication Status: ppublish
Publication Status: ppublish
Résumé
Standardized EEG patterns according to the American Clinical Neurophysiology Society (ACNS) ("highly malignant", "malignant" and "benign") demonstrated good correlation with outcome after cardiac arrest (CA). However, this approach relates to EEGs after target temperature management (TTM), and correlation to other recognized outcome predictors remains unknown.
To investigate the relationship between categorized EEG and other outcome predictors, during and after TTM, at different temperatures.
In a prospective adult CA registry between 01.2014 and 06.2017, EEG at day one and two after CA were reclassified into pre-defined categories. Correlations between EEG and clinical, biochemical, neurophysiological outcome predictors, and prognosis (CPC at three months; good: 1-2), were assessed.
Of 203 CA episodes, 31.5% were managed targeting 33 °C, 60.6% targeting 36 °C, and 7.9% with spontaneous temperature. "Highly malignant" EEG was found in 36.7% of patients at day one (predicting poor prognosis with 91% specificity -95%CI: 83%-97%-, and 63% sensitivity -95% CI: 53%-72%), and 27.1% at day two. "Benign" EEG occurred in 19.2% at day one (sensitivity to good prognosis: 35% -95%CI: 26%-46%-, positive predictive value: 89% -95% CI: 75%-97%), and in 33.2% at day two. Categorized EEG showed robust correlations with all prognostic predictors. Results were similar between EEGs recorded at day one or two, and, especially for poor prognosis, across TTM targets.
Standardized EEG categorization after CA shows strong correlation with other outcome predictors, without marked variation across EEG recording time or TTM targets, underscoring its prognostic role in a multimodal approach.
To investigate the relationship between categorized EEG and other outcome predictors, during and after TTM, at different temperatures.
In a prospective adult CA registry between 01.2014 and 06.2017, EEG at day one and two after CA were reclassified into pre-defined categories. Correlations between EEG and clinical, biochemical, neurophysiological outcome predictors, and prognosis (CPC at three months; good: 1-2), were assessed.
Of 203 CA episodes, 31.5% were managed targeting 33 °C, 60.6% targeting 36 °C, and 7.9% with spontaneous temperature. "Highly malignant" EEG was found in 36.7% of patients at day one (predicting poor prognosis with 91% specificity -95%CI: 83%-97%-, and 63% sensitivity -95% CI: 53%-72%), and 27.1% at day two. "Benign" EEG occurred in 19.2% at day one (sensitivity to good prognosis: 35% -95%CI: 26%-46%-, positive predictive value: 89% -95% CI: 75%-97%), and in 33.2% at day two. Categorized EEG showed robust correlations with all prognostic predictors. Results were similar between EEGs recorded at day one or two, and, especially for poor prognosis, across TTM targets.
Standardized EEG categorization after CA shows strong correlation with other outcome predictors, without marked variation across EEG recording time or TTM targets, underscoring its prognostic role in a multimodal approach.
Sujets
PID Serval
serval:BIB_3245D4F76685
PMID
Open Access
Oui
Date de création
2018-03-15T17:07:37.874Z
Date de création dans IRIS
2025-05-20T20:11:22Z
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Nom
29530626AM.pdf
Version du manuscrit
postprint
Taille
364.51 KB
Format
Adobe PDF
PID Serval
serval:BIB_3245D4F76685.P001
URN
urn:nbn:ch:serval-BIB_3245D4F766851
Somme de contrôle
(MD5):23d49db0cb4bdd2b786f23d37d7e0e11