Titre
Interferon-Produktion bei der akuten Virushepatitis [Interferon production in acute virus hepatitis].
Type
article
Institution
Externe
Périodique
Leber, Magen, Darm
Auteur(s)
Pirovino, M.
Auteure/Auteur
Aguet, M.
Auteure/Auteur
Huber, M.
Auteure/Auteur
Altorfer, J.
Auteure/Auteur
Schmid, M.
Auteure/Auteur
Liens vers les personnes
ISSN
0300-8622
Statut éditorial
Publié
Date de publication
1984
Volume
14
Numéro
6
Première page
258
Dernière page/numéro d’article
260
Langue
allemand
Notes
Publication types: English Abstract ; Journal Article
Résumé
Serum interferon activity was measured in 40 patients with acute viral hepatitis A, B and non-A-non-B during the acute stage of the disease and correlated with the severity, the long-term outcome and the viral etiology of the disease. Patients with alcoholic hepatitis, patients with an influenza-like illness and healthy volunteers served as controls. 80% of all patients with virus hepatitis revealed no measureable or only borderline interferon activity in their serum. No correlation was found with severity and long-term outcome of the disease, but patients with virus hepatitis A showed a stronger interferon induction than patients with hepatitis B and non-A-non-B. Further investigations of the interferon system in patients with virus hepatitis might help to improve our understanding of the different forms of the disease. The data presently available, however, do not permit as yet to define the value of interferon in the treatment of severe forms of acute virus hepatitis.
PID Serval
serval:BIB_2D3A358DD4A5
PMID
Date de création
2008-01-28T10:36:59.781Z
Date de création dans IRIS
2025-05-20T20:41:13Z