Titre
Comparative effectiveness research across two spine registries.
Type
article
Institution
UNIL/CHUV/Unisanté + institutions partenaires
Périodique
Auteur(s)
Aghayev, E.
Auteure/Auteur
Henning, J.
Auteure/Auteur
Munting, E.
Auteure/Auteur
Diel, P.
Auteure/Auteur
Moulin, P.
Auteure/Auteur
Röder, C.
Auteure/Auteur
Contributrices/contributeurs
Bärlocher, C.
Sgier, F.
Etter, C.
Hausmann, O.
Schwarzenbach, O.
Huber, J.
Aebi, M.
Heini, P.
Berlemann, U.
Markwalder, T.
Otten, P.
Schaeren, S.
Maestretti, GL.
Schizas, C.
Waelchli, B.
Porchet, F.
Baur, M.
Kast, E.
Seidel, U.
Lutz, T.
Grob, D.
Jeanneret, B.
Kroeber, M.
Min, K.
Hasdemir, M.
Lattig, F.
Morard, M.
Renella, R.
Richter, H.
Van Domelen, K.
Wernli, FO.
Binggeli, R.
Stoll, TM.
Marchesi, D.
Tessitore, E.
Vernet, O.
Faundez, A.
Favre, J.
Ramadan, A.
Selz, T.
Boos, N.
Cathrein, P.
Forster, T.
Heilbronner, R.
Kleinstueck, F.
Martinez, R.
Rischke, B.
Groupes de travail
SWISSspine
Spine Tango Registry groups
Liens vers les personnes
Liens vers les unités
ISSN
1432-0932
Statut éditorial
Publié
Date de publication
2012
Volume
21
Numéro
8
Première page
1640
Dernière page/numéro d’article
1647
Peer-reviewed
Oui
Langue
anglais
Notes
Publication types: Comparative Study ; Journal Article
Résumé
BACKGROUND: Comparative effectiveness research in spine surgery is still a rarity. In this study, pain alleviation and quality of life (QoL) improvement after lumbar total disc arthroplasty (TDA) and anterior lumbar interbody fusion (ALIF) were anonymously compared by surgeon and implant.
METHODS: A total of 534 monosegmental TDAs from the SWISSspine registry were analyzed. Mean age was 42 years (19-65 years), 59% were females. Fifty cases with ALIF were documented in the international Spine Tango registry and used as concurrent comparator group for the pain analysis. Mean age was 46 years (21-69 years), 78% were females. The average follow-up time in both samples was 1 year. Comparison of back/leg pain alleviation and QoL improvement was performed. Unadjusted and adjusted probabilities for achievement of minimum clinically relevant improvements of 18 VAS points or 0.25 EQ-5D points were calculated for each surgeon.
RESULTS: Mean preoperative back pain decreased from 69 to 30 points at 1 year (ØΔ 39pts) after TDA, and from 66 to 27 points after ALIF (ØΔ 39pts). Mean preoperative QoL improved from 0.34 to 0.74 points at 1 year (ØΔ 0.40pts). There were surgeons with better patient selection, indicated by lower adjusted probabilities reflecting worsening of outcomes if they had treated an average patient sample. ALIF had similar pain alleviation than TDA.
CONCLUSIONS: Pain alleviation after TDA and ALIF was similar. Differences in surgeon's patient selection based on pain and QoL were revealed. Some surgeons seem to miss the full therapeutic potential of TDA by selecting patients with lower symptom severity.
METHODS: A total of 534 monosegmental TDAs from the SWISSspine registry were analyzed. Mean age was 42 years (19-65 years), 59% were females. Fifty cases with ALIF were documented in the international Spine Tango registry and used as concurrent comparator group for the pain analysis. Mean age was 46 years (21-69 years), 78% were females. The average follow-up time in both samples was 1 year. Comparison of back/leg pain alleviation and QoL improvement was performed. Unadjusted and adjusted probabilities for achievement of minimum clinically relevant improvements of 18 VAS points or 0.25 EQ-5D points were calculated for each surgeon.
RESULTS: Mean preoperative back pain decreased from 69 to 30 points at 1 year (ØΔ 39pts) after TDA, and from 66 to 27 points after ALIF (ØΔ 39pts). Mean preoperative QoL improved from 0.34 to 0.74 points at 1 year (ØΔ 0.40pts). There were surgeons with better patient selection, indicated by lower adjusted probabilities reflecting worsening of outcomes if they had treated an average patient sample. ALIF had similar pain alleviation than TDA.
CONCLUSIONS: Pain alleviation after TDA and ALIF was similar. Differences in surgeon's patient selection based on pain and QoL were revealed. Some surgeons seem to miss the full therapeutic potential of TDA by selecting patients with lower symptom severity.
PID Serval
serval:BIB_3206A87BB467
PMID
Date de création
2013-01-25T14:17:55.449Z
Date de création dans IRIS
2025-05-20T19:15:49Z